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CA1

·December 3, 2025·7 min read

Hidden Brain Layers Revealed in Key Memory Center

Scientists have identified a previously unseen layered organization inside one of the brain’s most important memory hubs. The CA1 region of the hippocampus was found to contain four distinct bands of neuron types, each defined by unique genetic signatures that shift subtly across the structure.

Featured Neuroscience

·July 15, 2022·3 min read

Neuronal Cell Type for Controlling the Flow of Information in the Brain Discovered

By briefly inhibiting other cells, neurogliaform cells in the CA1 region of the hippocampus ensure that current perception and memories of past experiences can be processed both separately and in combination with each other.

This shows the outline of a woman's head and brain

Featured Neuroscience

·April 11, 2022·8 min read

A Single Memory Is Stored Across Many Connected Brain Regions

Brain mapping study reveals memory engrams are widely distributed throughout the brain, including among regions not previously realized.

Featured Genetics Neuroscience

·March 17, 2022·6 min read

Long-Suspected Turbocharger for Memory Found in Brain Cells of Mice

Floods of calcium that originate from hippocampal neurons can also boost learning, a new study reports.

Featured Neuroscience Open Neuroscience Articles

·February 9, 2022·3 min read

How Left and Right Hippocampal CA1 Regions in the Mouse Brain Talk With Each Other

Researchers have uncovered neural circuitry that allows the CA1 region of the hippocampus to communicate with its counterpart in the opposite hemisphere despite there being no connection between them.

This shows a finger touching a picture of a brain

Featured Neuroscience Open Neuroscience Articles

·September 16, 2021·3 min read

Drug Targets for Memory Enhancement

Researchers identified specific receptors for acetylcholine that reroute information flow through memory circuits in the hippocampus. The findings could have implications for the development of drugs to help enhance or protect memory from diseases associated with cognitive decline.

Electrophysiology Featured Neuroscience

·September 4, 2021·3 min read

Early Changes to the Extracellular Space in the Hippocampus Under Simulated Microgravity Conditions

Findings shed light on the mechanisms underlying brain damage in microgravity.

Featured Neuroscience

·February 15, 2021·5 min read

Peeking at the Pathfinding Strategies of the Hippocampus

Researchers observed hippocampal place cell changes in animal experiments of cue-poor and cue-rich spatial environments. The findings have implications for the treatment of brain disorders and the development of new AI technologies.

This shows pyramidal cells in the CA2 of the hippocampus

Featured Neuroscience

·January 11, 2021·6 min read

Brain Circuit That Encodes Timing of Events Identified

Pyramidal cells in the CA2 region of the hippocampus are responsible for storing critical timing information.

Featured Neuroscience

·December 28, 2020·4 min read

Astrocytes Eat Connections to Maintain Plasticity in Adult Brains

Astrocytes, not microglia, are responsible for constantly eliminating unnecessary and excessive adult synaptic connections in response to brain activity.

Featured Neuroscience Open Neuroscience Articles

·June 12, 2020·3 min read

Inhibitory interneurons in hippocampus excite the developing brain

GABAergic interneuron excitation is essential for network activity in the hippocampus of the fetal brain.

Featured Neurology Neuroscience

·June 9, 2020·4 min read

Noise-inducing neurons shut down memories in Alzheimer’s

In mouse models of Alzheimer's disease, active neurons still encode memory, and a group of active neurons encodes novel environmental information. The signal of the novelty containing neurons causes a superimposition disturbing the signal of memory encoding neurons.

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CA1

Hidden Brain Layers Revealed in Key Memory Center

Neuronal Cell Type for Controlling the Flow of Information in the Brain Discovered

A Single Memory Is Stored Across Many Connected Brain Regions

Long-Suspected Turbocharger for Memory Found in Brain Cells of Mice

How Left and Right Hippocampal CA1 Regions in the Mouse Brain Talk With Each Other

Drug Targets for Memory Enhancement

Early Changes to the Extracellular Space in the Hippocampus Under Simulated Microgravity Conditions

Peeking at the Pathfinding Strategies of the Hippocampus

Brain Circuit That Encodes Timing of Events Identified

Astrocytes Eat Connections to Maintain Plasticity in Adult Brains

Inhibitory interneurons in hippocampus excite the developing brain

Noise-inducing neurons shut down memories in Alzheimer’s

Brain Stimulation Method Can Evaluate Consciousness in Alzheimer’s Disease

Early Intervention Helps Most Autistic Children Acquire Spoken Language

Brain Conductors Find Precise Connection to Target Cells via Protein Handshake

Multilingualism Calculator Reveals True Language Strengths

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