Frequently, as many as one thousand signals rain down on a single neuron simultaneously. To ensure that precise signals are delivered, the brain possesses a sophisticated inhibitory system. Scientists have now illuminated how this system works.
Researchers have identified a possible new drug target that could help to restore memory loss and improve longevity in Alzheimer's disease.
Using a technique called parabiosis on pairs of mice, researchers discover what they call 'cancer like mobility' of amyloid beta, reporting it can travel to the brain from other parts of the body.
Astrocytes, not microglia, are responsible for constantly eliminating unnecessary and excessive adult synaptic connections in response to brain activity.
Neuroscientists found that astrocytes may be responsible for the rapid improvement in mood in depressed patients after acute sleep deprivation. This study identified how astrocytes can regulate a neurotransmitter involved in sleep.
Researchers identify a neural circuit that connects the hippocampus and the entorhinal cortex, which is responsible for encoding episodic memory.
Pyramidal cells in the CA2 region of the hippocampus are responsible for storing critical timing information.
Researchers report episodic memory function becomes disrupted when neural pathways that allow communication between the hippocampus and prefrontal cortex are deactivated.
Multisensory gamma wave stimulation improves recognition and spatial memory, in addition to reducing amyloid in the auditory cortex and hippocampal CA1 areas of mice. Findings suggest such sensory stimulation boosts hippocampal function and reduces Alzheimer's linked pathologies throughout the neocortex.