Infiltrating gliomas are shaped by their genetic evolution and microenvironment, researchers report. The findings may help in the development of therapies to treat glioma brain tumors.
Asthma causes T cells to induce lung inflammation but prevents the growth of brain tumors. Reprogramming T cells in patients with brain cancer to act like T cells in those with asthma may help to curb the growth of tumors.
Researchers have successfully replicated an entire, viable glioblastoma brain tumor via 3D bioprinting. The bioprinted tumor includes a complex system of blood vessel-like tubes through which blood cells and drug molecules can flow, simulating a real tumor.
Glioblastoma can mimic the normal repair of white matter in the brain, causing the tumor to become less malignant. Additionally, a drug commonly prescribed for asthma can help suppress glioblastoma growth in mouse models.
Researchers have identified specific characteristics of vestibular schwannomas in children. While children have similar symptoms of the brain tumors as experienced by adults, the tumor size was typically larger in pediatric patients at the time of diagnosis.
Glioma brain tumors alter the function of astrocytes, possibly contributing to seizures many brain cancer patients experience. Astrocytes encasing gliomas exhibit different molecular signatures based on their proximity to the cancer cells. Those directly touching the cancer cells become elongated and swollen, mimicking the astrocyte's response to other epilepsy-related brain injuries.
After a single session of transcranial electrical stimulation (tES), researchers noted a significant reduction in blood flow to brain tumors. However, there were no alterations in blood flow or activity in the rest of the brain. The technique may be helpful in the treatment of brain cancers such as glioblastoma.