Researchers believe their findings could lead to new targets for brain cancer therapies. Read More
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A new probe developed uses an innovative fluorescence-reading technology to help brain surgeons distinguish cancerous tissue from normal tissue. The probe tool, now already in use at the Cancer Center for brain surgery, may one day be used for surgeries for a variety of cancers. Read More
Researchers at the Stanford University School of Medicine and Lucile Packard Children’s Hospital have identified several gene mutations responsible for the most common childhood brain tumor, called medulloblastoma, adding evidence to the theory that the diagnosis is a group of genetically distinct cancers with different prognoses. These and accompanying findings are likely to lead to less toxic, better targeted treatment approaches over the next two years, the researchers said. Read More
Researchers discovered that some cases of glioblastoma, the most common and aggressive form of primary brain cancer, are caused by the fusion of two adjacent genes. The study also found that drugs that target the protein produced by this genetic aberration can dramatically slow the growth of glioblastomas in mice. Read More
A new study reveals how the physical force exerted by the solid components of brain tumors impacts surrounding tissue, resulting in apoptosis and neurological dysfunction. Researchers reports the drug lithium, commonly prescribed for bipolar disorder, can help reverse some of the damage caused by the solid stress of the tumor. Read More
Scientists showed in mice that disabling a gene linked to a common pediatric tumor disorder, neurofibromatosis type 1 (NF1), made stem cells from one part of the brain proliferate rapidly. But the same genetic deficit had no effect on stem cells from another brain region. Read More
Researchers discover the genetic landscape of the most common form of brain tumor can be explained by abnormalities in five genes. The finding could help to develop personalized medical therapies and treatment options. Read More
Researchers at The University of Nottingham have identified three sets of genetic markers that could potentially pave the way for... Read More
U-M scientists stop abnormal brain cell growth in mice with neurofibromatosis using experimental tumor drug, make new discoveries in neural stem cells. Read More
Johns Hopkins scientists hope discovery will drive drug treatments. Johns Hopkins researchers say they have discovered one of the most... Read More
“We identified a subset of brain tumor cells that are slower growing or remain at rest, and appear to be the source of cancer recurrence after standard therapy in which the drug temozolomide is given to stop the tumor’s growth,” said Dr. Luis Parada. “Current therapy targets fast-growing tumor cells but not those responsible for new tumors. To the best of our knowledge, this is the first identification of a cancer stem-like cell in a spontaneously forming tumor inside a mammal.” Read More
Scientists have discovered genetic mutations in brain tumors that alter brain tumor metabolism. The scientists report that cells with defective... Read More
