Researchers have developed a new method to create glutamatergic neuronal cells from SH-SY5Y cells without the use of animal-derived components. The new technique repurposes the B-27 growth supplement. This is the first time SH-SY5Y cells have been transformed into glutamatergic neuronal cells, researchers report.
Study identifies rare brain cell types that are unique to male mice, and others that are unique to females. The cells were discovered in the hypothalamus, a region of the brain that governs both aggression and mating behaviors.
Researchers from Allen Institute have released a publicly available database of live human brain cells. The data is comprised of samples taken from neurosurgery patients and includes over 300 living cortical neurons of different types.
Inflammation in the brain prevents cells from accessing the iron they need in order to perform a critical role in neurodevelopment.
Mutations of a gene associated with some forms of autism in humans can hinder the correct growth and connectivity of neurons in mice. This understanding allowed researchers to restore proper neuronal growth in the mice.
A new study points to a newly discovered system in which the brain removed waste as a potential new tool to treat neurodegenerative disorders.
Researchers develop a flexible carbon-nanotube 'harpoon' to study individual brain neurons. The 'brain harpoon' harnesses the electromechanical properties of carbon nanotubes to capture the electrical signals generated by single neurons.
Researchers have mapped the activity of brain cells in the mushroom body of flies conditioned to have Pavlovian behavioral responses to different odors. The findings suggest the activity of as few as 25 neurons are required to be able to distinguish between different odors.
New research identifies a pair of neurons which control the feeding behavior in Drosophila fruit flies. The discovery could help scientists better understand how the brain uses stimuli and memory to produce classically conditioned responses.
Researchers find a fruit fly's salty taste sensation strategy could apply to other animals, even humans.
Researchers discover presenilin, a protein associated with Alzheimer's disease, controls the speed at which materials move through brain cells. Defects in presenilin could lead to neuronal blockages with amyloid plaques, commonly associated with this neurodegenerative disorder.
Researchers discover a population of cells, called tanycytes, are capable of generating new appetite regulating neurons in the brains of both young and adult rodents. The discovery could offer new avenues for tackling obesity.