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ApoE4

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·September 16, 2019·4 min read

Alzheimer’s disease risk gene APOE4 impairs function of brain immune cells

APOE4 increases the inflammatory response of human microglia while reducing cellular migration. The gene also impairs the metabolic activity of the immune cells. The findings show APOE4 has a profound impact on the basic functions of microglia.

Featured Neurology Neuroscience

·September 13, 2019·3 min read

What multilingual nuns can tell us about dementia

While being multilingual did not delay the onset of dementia for those at risk, nuns who spoke four or more languages were significantly less likely to develop dementia than those who spoke just one language.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·August 22, 2019·4 min read

Carriers of Alzheimer’s genetic marker have greater difficulty harnessing past knowledge

Middle-aged people with the Alzheimer's related APOE4 gene have a harder time accessing recently acquired knowledge, even when they show no symptoms of memory decline.

This shows a researcher performing analyzes of blood work

Featured Neurology Neuroscience

·August 2, 2019·6 min read

Blood test 94% accurate at identifying Alzheimer’s before symptoms appear

A new blood test for Alzheimer's disease is up-to 94% accurate at predicting dementia before symptoms appear. The test's accuracy is increased when genetic predisposition and age are taken into account. The new test may eventually replace PET neuroimaging, currently considered the gold standard, for early detection of Alzheimer's.

Featured Genetics Neurology Neuroscience

·July 20, 2019·3 min read

Lower childhood IQ linked to Alzheimer’s later in life

Children with the APOE E4 gene perform lower on verbal and general IQ tests than their peers without the genetic risk factor. APOE E4 is a genetic risk factor for Alzheimer's disease. The study suggests the effects of the gene manifests before adulthood and could be the earliest biomarker for later vulnerability to Alzheimer's disease.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·June 27, 2019·3 min read

Dementia study links gene with damage to brain connections

Post mortem examinations of brain tissue from Alzheimer's patients revealed synapses contained clumps of clusterin, in addition to amyloid beta. The clumps were more abundant in those with genetic risk factors from Alzheimer's disease.

Featured Neurology Neuroscience

·January 7, 2019·7 min read

Racial Differences in Alzheimer’s Unveiled

A new study has identified racial disparities between African Americans and Caucasians in the level of a key biomarker used to identify Alzheimer's disease.

Featured Neurology Neuroscience Open Neuroscience Articles

·December 17, 2018·3 min read

A Pathway to a Vaccine and Drugs for Late Onset Alzheimer’s

Researchers have successfully neutralized a genetic risk factor found in up to 80% of Alzheimer's patients. The ability to neutralize ApoE4 could help in the development of a vaccine, as well as other therapeutics, for late onset Alzheimer's.

Featured Genetics Neurology

·December 5, 2018·5 min read

Alzheimer’s Patients Classified in Six Subgroups

Researchers have identified cognitive subgroups related to genetic differences in Alzheimer's patients. The findings, researchers say, could open the door for more personalized treatments of the neurodegenerative disease.

Featured Neurology Neuroscience

·November 21, 2018·3 min read

Researchers Use MRI to Predict Alzheimer’s

Using neuroimaging technology to examine white matter tracts in the brain, researchers were able to diagnose Alzheimer's disease with 95% accuracy.

Featured Neurology Open Neuroscience Articles

·October 20, 2018·4 min read

Chronic Inflammation Linked to Increased Risk of Alzheimer’s

A new study reveals carriers of the ApoE4 gene who have chronic inflammation are more likely to develop Alzheimer's disease.

Featured Neurology Open Neuroscience Articles

·October 19, 2018·5 min read

Does Herpes Cause Alzheimer’s?

A new study looks at the possible causal link between the herpes virus and Alzheimer's disease. Researchers report antiviral drugs significantly reduce the risk of developing dementia in patients with severe herpes infections.

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ApoE4

Alzheimer’s disease risk gene APOE4 impairs function of brain immune cells

What multilingual nuns can tell us about dementia

Carriers of Alzheimer’s genetic marker have greater difficulty harnessing past knowledge

Blood test 94% accurate at identifying Alzheimer’s before symptoms appear

Lower childhood IQ linked to Alzheimer’s later in life

Dementia study links gene with damage to brain connections

Racial Differences in Alzheimer’s Unveiled

A Pathway to a Vaccine and Drugs for Late Onset Alzheimer’s

Alzheimer’s Patients Classified in Six Subgroups

Researchers Use MRI to Predict Alzheimer’s

Chronic Inflammation Linked to Increased Risk of Alzheimer’s

Does Herpes Cause Alzheimer’s?

Cell Membrane Lipid Governs Retinal Light Sensitivity

Dogs Parse Human Speech Using the Same Consonant Bias as Humans

Solving the Mystery of the Smooth Primate Brain

Can Humor Treat Depression?

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