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ApoE4

This image is a drawing of a brain slice from an Alzheimer's patient.

·May 14, 2015·4 min read

Major Alzheimer’s Risk Gene Opens New Pathway to Prevention

Researchers report ApoE4 can reduce the number of functional synapses by interfering with the DNA responsible for synapse formation and maintenance.

This shows blood being drawn from a finger.

Featured Neurology

·March 9, 2014·4 min read

Blood Test Identifies Those at Risk for Cognitive Decline and Alzheimer’s Within 3 Years

Researchers have created and validated a blood test which can, with 90 percent accuracy, predict if a healthy person will develop AD within 3 years.

The image is a diagram comparing the difference between neuron damage and associated damage in alzheimer's disease with normal neurons.

Featured Neurology

·November 20, 2013·5 min read

Study Reveals How Variant Forms of APOE Protein Impact Risk of Alzheimer’s Disease

A new study reports even low levels of APOE4 can increase beta-amyloid plaques in the brain and neuronal damage in mouse models of Alzheimer's disease. However, introducing APOE2 can reduce amyloid deposits and other associated damage.

The image is a diagram showing the formation of beta-amyloid.

Featured Neurology

·October 21, 2013·3 min read

Major Alzheimer’s Risk Factor Linked to Red Wine Target

A new study provides insight into the link between ApoE4 and SirT1, an anti-aging protein found is resveratrol.

This image shows the networks in the brain as addressed in the research article.

Featured Neurology

·September 20, 2013·2 min read

Memory Related Brain Network Shrinks with Aging

Researchers find brain regions associated with memory shrink as adults age. This decrease in size is more pronounced in those who later develop neurodegenerative diseases, such as Alzheimer's.

This is a schematic of the Alzheimer's gene expression.

Featured Genetics

·July 24, 2013·4 min read

Key Molecular Pathways Leading to Alzheimer’s Identified

Researchers have identified key molecular pathways which lead to late-onset Alzheimer's disease. The study presents a new approach to Alzheimer's research and highlights several potential drug targets.