A new discovery could help answer the question as to how extra ApoE4 may cause Alzheimer's disease.
A new study sheds light into the link between lifestyle and the risk of developing dementia.
Stem cell study reveals astrocytes carrying the Alzheimer's associated APOE4 gene release more cholesterol than those carrying the APOE3 gene. Findings shed light on how different versions of the APOE gene in astrocytes influence amyloid-beta production and how the oversupply of cholesterol associated with APOE4 astrocytes may promote amyloid-beta formation in Alzheimer's patients.
Researchers are testing whether low doses of Rapamycin, a drug most commonly used as an immunosuppressant following an organ transplant, can help to prevent Alzheimer's disease.
A gene variant responsible for vascular damage to the brain is a promising new target for drug therapy to fight...
A new mouse study finds APOE genes, commonly associated with Alzheimer's disease, impairs the development of new neurons in areas of the brain associated with memory.
Researchers have created and validated a blood test which can, with 90 percent accuracy, predict if a healthy person will develop AD within 3 years.
Researchers report ApoE4 can reduce the number of functional synapses by interfering with the DNA responsible for synapse formation and maintenance.
Researchers report a link between a lower BMI and greater deposits of amyloid plaques in older individuals.
APOE4 affects lipid metabolism, but taking choline supplements may help protect carriers from developing Alzheimer's disease and slow cognitive decline.
ApoE4, a gene associated with an increased risk of Alzheimer's disease, also appears to increase susceptibility and the severity of COVID-19. SARS-CoV-2, the virus responsible for coronavirus, increased susceptibility to COVID-19 in ApoE4 neurons and astrocytes in brain organoid models.
People with higher levels of omega-3 DHA in their blood are 49% less likely to develop dementia than those with lower levels. Researchers say adding additional omega-3 DHA to the diet, especially in those with the Alzheimer's associated Apoe4 gene, could slow the development and progress of dementia.
