FeaturedNeurology·May 10, 2013·3 min readCancer Drug Prevents Build-up of Toxic Brain ProteinUsing a tiny dose of the leukemia drug nilotinib, researchers halt the accumulation of toxic proteins linked to Parkinson's diseases in the brains of mice.Read More
FeaturedNeurology·April 23, 2013·4 min readALS Trial Shows Novel Therapy is SafeA new treatment for ALS, which uses a technique that turns off the mutated SOD1 gene, has passed an early phase clinical trial for safety.Read More
FeaturedGenetics·March 3, 2013·5 min readTwo New Genes Linked to ALS and Related Neurodegenerative DisordersA new study ties mutations in two genes to the death of nerve cells in amyotrophic lateral sclerosis (ALS) and other related neurodegenerative diseases.Read More
FeaturedNeurology·March 1, 2013·3 min readMisplaced Molecules: New Insights into the Causes of DementiaNew research supports the idea that a malfunction of the TDP-43 protein plays a decisive role in the development of ALS and FTD.Read More
FeaturedNeurology·February 12, 2013·3 min readNovel Protein May Help Detect Lou Gehrig’s Disease and DementiaResearchers discover an abnormal protein that accumulates in the brains of patients affected with ALS and frontotemporal dementia. The findings have uncovered a potentially new therapeutic target and biomarker that would allow clinicians to confirm diagnosis of the diseases.Read More
FeaturedNeurology·February 5, 2013·3 min readStudy Confirms No Transmission of Alzheimer’s Proteins Between HumansWhile evidence suggests pathological proteins linked to the onset and progression of neurodegenerative disorders are capable of spreading from cell-to-cell within the brains of affected individuals, new research shows no evidence to support concerns that these abnormal disease proteins are “infectious” or transmitted from animals to humans or from one person to another.Read More
FeaturedNeuroscience·January 21, 2013·3 min readResearchers Turn One Form of Neuron into Another in the BrainA new finding turns one of the basics of neurobiology on its head, demonstrating that it is possible to turn one type of already differentiated neuron into another within the brain.Read More
FeaturedGenetics·January 15, 2013·2 min readResearchers Identify New Genetic Mutation for ALSResearchers have identified a new genetic mutation for amyotrophic lateral sclerosis (ALS), opening the door to future targeted therapies.Read More
FeaturedNeurology·October 2, 2012·2 min readNew Research Model to Aid Search for Degenerative Disease CuresEfforts to treat disorders like Lou Gehrig’s disease, Paget’s disease, inclusion body myopathy and dementia will receive a considerable boost from a new research model created by UC Irvine scientists.Read More
FeaturedNeurology·September 5, 2012·2 min readNFL Players May Be at Higher Risk of Death from Alzheimer’s and ALSProfessional football players in this study were three times more likely to die as a result of diseases that damage brain cells compared to the general population. A player’s risk of death from Alzheimer’s disease or ALS was almost four times higher than the general population.Read More
FeaturedNeurologyOpen Neuroscience Articles·August 31, 2012·5 min readResearchers Identify Potential New Approach for Improving Quality of Life for ALS PatientsBy increasing the signaling activity of a protein called muscle skeletal receptor tyrosine-protein kinase (MuSK), researchers were able to keep nerve cells attached to muscle longer into the progression of the disease in a mouse model of ALS.Read More
FeaturedGeneticsNeurology·August 2, 2012·3 min readResearchers Find Genetic Cause for Body TremorsScientists knew that mutations in the FUS gene (Fused in Sarcoma) cause amyotrophic lateral sclerosis (ALS), a disease of the nerve cells in the brain and spinal cord that control voluntary muscle movement. The researchers were successful in identifying mutations in this gene that cause Essential Tremor, and proved that the disease mechanisms for ET and ALS FUS mutations are different.Read More
