Using neurons created from iPS cells derived from people with ALS, researchers develop a new drug which appears to halt the impact of the genetic mutations in some forms of ALS and dementia.
Microglia plays crucial roles both in healthy and diseased brains, a new study reports.
Mislocalization of the TDP-43 protein alters the genetic instructions for UNC13A. The findings provide a potential new therapeutic target for the treatment of ALS and frontotemporal dementia.
A new study reports on the role the protein TDP-43 plays in the development of Alzheimer's disease.
Gene expressions in the brain that occur early in development may explain why some cerebellar stem cell populations behave differently in people with SCA1, researchers report.
A new study reports people with ALs may have a genetic mutation that causes SOD1 to aggregate motor neurons in the brain and spinal cord.
Study shows how ALS may impact neurons as they mature.
A new discovery could speed identification of ALS in patients.
A new study points to a potential new target to treat neurodegenerative diseases.
Astrocyte toxicity in ALS may be caused by an explicit loss on MHCI expression in motor neurons, a new study reveals.
Researchers discovered both immune system and central nervous system dysfunction in animal models and people with ALS4, a genetic, juvenile, and slow-progressing form of ALS.
NU-9, a novel, non-toxic compound, targets upper motor neurons and reverses damage associated with ALS within 60 days of treatment.
