Researchers have identified a modifier gene that affects the risk of developing degenerative myelopathy, a canine disease similar to ALS in Welsh corgis.
A new study cancer suppression proteins play key roles in the progression of ALS.
A new study reports cumulative pesticide exposure is linked to an increased risk for developing ALS.
New research could help scientist better understand the role of astrocytes in neurodegenerative diseases.
Researchers have identified the normal function of C9orf72, a gene commonly implicated in ALS and FTD.
Scientists knew that mutations in the FUS gene (Fused in Sarcoma) cause amyotrophic lateral sclerosis (ALS), a disease of the nerve cells in the brain and spinal cord that control voluntary muscle movement. The researchers were successful in identifying mutations in this gene that cause Essential Tremor, and proved that the disease mechanisms for ET and ALS FUS mutations are different.
Researchers reveal a repeat element in the DNA of C9orf72 gene becomes toxic when faced with starvation, toxins and viral infection.
Researchers have discovered a potential treatment that may help delay motor neuron loss in ALS.
UC Berkeley researchers report they have successfully used CRISPR-Cas9 gene editing to delay symptoms and extend lifespan in mouse models of ALS.
According to new research, the C9orf72 mutation causes long strands of RNA to block specific pathways which usually move proteins into a cell's nucleus.
In patients with ALS, astrocytes within the brain become pro-inflammatory and tend to lose their protective function, resulting in changes in the ability to uptake glutamate.
Summary: Researchers discover a specific genetic mutation in approximately 17% of people with ALS who report no family history of...
