FeaturedNeurologyNeuroscience·May 1, 2022·4 min readNew Blood Biomarker for Predicting Dementia Before Symptoms DevelopMeasuring blood levels of P-tau181 may allow doctors to diagnose Alzheimer's before the onset of symptoms. Elevated levels of P-tau181 in the blood were associated with greater amyloid beta accumulation in the brain and outperformed two other biomarkers in predicting signs of amyloid beta in brain scans.Read More
FeaturedGeneticsNeurologyNeuroscience·April 20, 2022·5 min readSingle-Cell DNA Sequencing Offers a New Angle on the Causes of Alzheimer’s DiseaseAn abundance of newly acquired mutations in the mutations that occur at an accelerated speed is a telling pattern of Alzheimer's disease, researchers report.Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience ArticlesPsychology·April 19, 2022·4 min readPsychiatric Symptoms in Alzheimer’s DiseaseLike cognitive deficits, psychiatric symptoms such as depression, apathy, and anxiety associated with Alzheimer's disease appear to be a direct consequence of underlying brain changes as a result of increased amyloid-beta accumulation.Read More
FeaturedNeurologyNeuroscience·March 2, 2022·2 min readDrug Candidate Reduced Brain Inflammation and Protected Against Cognitive Decline in Alzheimer’s Mouse Model3,6’-dithiopomalidomide (DP), an anti-inflammatory drug candidate, protected mouse models of Alzheimer's disease against cognitive decline by reducing neuroinflammation.Read More
FeaturedNeurologyNeuroscience·February 24, 2022·3 min readHaving a Poor Score on a Simple Memory Test May Be Linked to Alzheimer’s BiomarkersEven for older people experiencing no general memory or thinking problems, performing poorly on a simple memory test may be linked to biomarkers for Alzheimer's disease.Read More
FeaturedGeneticsNeurologyNeuroscience·February 2, 2022·4 min readNew Non-Mutated Protein Linked to DementiaAPOE proteins were enhanced in the brains of patients with dementia, even when they did not carry the Alzheimer's associated gene.Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·January 13, 2022·3 min readHeart Disease Causes Early Brain Dysfunction and Can Treble Key Alzheimer’s ProteinHeart disease that causes brain dysfunction can lead to the development of Alzheimer's disease and triples the amount of amyloid-beta in the brain.Read More
FeaturedGeneticsNeurologyNeuroscience·December 22, 2021·7 min readNew Alzheimer’s Prevention Trial in Young PeopleA new international clinical trial has been launched with an aim of preventing Alzheimer's disease in people with a genetic disposition who are likely to develop the disease at a younger age.Read More
FeaturedGeneticsNeurologyNeuroscience·December 20, 2021·2 min readTwins Study Indicates Environmental Factors Significant in Alzheimer’s PathologyGenes only play a moderate role in the accumulation of amyloid beta in the brain.Read More
FeaturedNeurologyNeuroscience·December 2, 2021·5 min readImmune Cells in the Brain Play Key Role in Relationship Between Gut Microbes and Amyloid Beta DepositsMicroglia, a key immune cell in the brain, appears to mediate the relationship between the gut microbiome and amyloid-beta deposits in male mouse models of Alzheimer's disease.Read More
FeaturedNeurologyNeuroscience·November 27, 2021·5 min readNew Framework for Analyzing Alzheimer’s Disease Identifies Not One Form, but ThreeA new framework reveals Alzheimer's disease is far more complex than previously believed. Rather than being a disease where the same causes produce the same outcomes, researchers found three different models for the disease, each with its own characterizations and dynamics.Read More
FeaturedNeurologyNeuroscience·November 19, 2021·3 min readDisrupted Circadian Regulation of Cognition in Alzheimer’s DiseaseAmyloid-beta accumulation in the brain may contribute to deficits in circadian regulation of learning and memory during the early stages of Alzheimer's disease.Read More
