FeaturedNeurology·July 27, 2020·5 min readFlu and Pneumonia Vaccinations Tied to Lower Risk of Alzheimer’sBeing vaccinated against influenza was associated with a 17% reduction in Alzheimer's incidence. Pneumonia vaccinations given between the ages of 65 and 75, reduced Alzheimer's risk by up to 40%.Read More
FeaturedNeurology·July 20, 2020·3 min readOlder Adults Who Can Really Smell the Roses May Face Lower Likelihood of DementiaOlder adults with a higher ability to process sensations, including vision, olfaction, hearing, and touch, had half the risk of being diagnosed with cognitive decline than their peers who were less capable at sensory processing tasks.Read More
FeaturedNeurology·July 20, 2020·4 min readOxytocin Could Be Used to Treat Cognitive Disorders Like Alzheimer’sOxytocin, the so-called "love hormone," could help to treat cognitive disorders, including Alzheimer's disease. Researchers demonstrated oxytocin reversed the effects of amyloid-beta on hippocampal LTP in mice. The findings suggest oxytocin could be used as a therapeutic for the treatment of Alzheimer's disease and other dementias.Read More
FeaturedGeneticsNeurologyOpen Neuroscience Articles·July 18, 2020·5 min readAdults With Alzheimer’s Risk Factors Show Subtle Alterations in Brain Networks Despite Normal CognitionAPOEe4, a gene associated with Alzheimer's disease risk, doesn't appear to directly affect memory performance or brain activity in older adults without cognitive impairment. However, the gene does seem to influence brain regions and systems that older at-risk adults activate to support successful memory recall.Read More
FeaturedGeneticsNeurologyNeurosciencePsychology·July 17, 2020·4 min readSynapse-Saving Proteins Discovered, Opening Possibilities in Alzheimer’s and SchizophreniaStudy identified a new class of proteins that protect synapses from being destroyed. The findings have important implications for both Alzheimer's disease and schizophrenia.Read More
FeaturedNeurology·July 16, 2020·5 min readA “Feeling” for Dementia?People with subjectively felt memory deficits also exhibited measurable cognitive deficits that were associated with abnormalities in spinal fluid.Read More
FeaturedNeurologyOpen Neuroscience Articles·July 15, 2020·5 min readDopamine Therapy Improves Cognitive Function in Alzheimer’sRotigotine, a drug that acts on dopamine transmission, improves cognitive function in patients with mild-to-moderate Alzheimer's disease. While the drug did not help improve memory, it did improve executive function in the frontal lobe and positively impacted the ability of patients to perform activities of daily living.Read More
FeaturedNeurologyOpen Neuroscience Articles·July 3, 2020·5 min readBrain Iron Accumulation Linked to Cognitive Decline in Alzheimer’sIron accumulation in the brain's neocortex has been linked to cognitive decline in people with Alzheimer's disease.Read More
FeaturedNeurology·July 1, 2020·5 min readAsthma Drug Salbutamol a Potential Alzheimer’s TreatmentSalbutamol, a common asthma medication, shows potential for the treatment of Alzheimer's disease. The drug is effective at reducing the accumulation of insoluble fibers of the tau protein.Read More
FeaturedGeneticsOpen Neuroscience Articles·June 24, 2020·5 min readProtein in mitochondria appears to regulate health and longevityHumanin, a peptide encoded in mitochondria, appears to have a beneficial impact on both health and longevity in both humans and animals. Higher levels of humanin in the body are associated with longer life spans and a reduced risk of neurodegenerative disorders, like Alzheimer's disease.Read More
FeaturedNeurologyOpen Neuroscience Articles·June 24, 2020·4 min readPulse pressure: A game changer in the fight against dementiaElevated pulse pressure in blood traveling to the brain causes inflammation, oxidative stress, and apoptosis in the blood-brain barrier that leads to brain damage.Read More
FeaturedGeneticsNeurology·June 23, 2020·5 min readNew gene may drive earliest brain changes in Alzheimer’sGenetic analysis of almost 4,300 samples reveals a link between the appearance of amyloid deposits, APOE, and a novel gene called RBFOX1. Lower levels of RBFOX1 in the brain appear to be associated with increased amyloid and global cognitive decline over a person's lifetime.Read More