The extracts of certain plants long used by Native Americans as topical analgesics activate the KCNQ2/3 potassium channel. The compounds provide pain relief and prevent diarrhea.
A new rodent study uncovers a neural circuit in the brain that appears to govern pain-induced anhedonia. Altering the activity of this circuit restored motivation in pre-clinical models of pain.
Study reveals a causal mechanism for pain reduction may be due to an antibiotic-induced shift in the gut's amino acid concentrations.
A four-week course of pain reprocessing therapy (PRT) provided up to 12 months of relief from pain for chronic pain sufferers. Additionally, the psychological treatment program altered brain networks associated with pain processing.
Widespread pain, a subset of chronic pain associated with musculoskeletal disorders, is linked to an increased risk of all types of dementias, including Alzheimer's disease, and a greater risk of stroke.
Cancer patients with vitamin D deficiency under palliative care reported a decreased need for opioids to control pain and reduced symptoms of fatigue when given vitamin D supplementation.