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          Pain

          Pain Neuroscience news articles cover science research about pain receptors, nociceptors, nociception, sensory neurons, somatosensory cortex, chronic pain, acute pain, nocioceptors, musculoskeletal pain, therapies, phantom limb pain and other pain research.

          This shows a neuron.
          FeaturedNeurologyNeurosciencePain
          ·August 20, 2024·3 min read

          Molecule Discovery Could Revolutionize Chronic Pain Treatment

          Researchers have identified a natural molecule, phosphatidic acid, that reduces the sensitivity of touch-sensing ion channels, providing a promising new avenue for managing chronic pain. By increasing levels of this molecule, cells become less sensitive to touch, which was confirmed through tests on sensory neurons and in mice. This discovery could lead to more targeted and effective treatments for conditions involving inflammatory pain.
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          This shows a brain.
          FeaturedNeurologyNeurosciencePain
          ·July 13, 2024·5 min read

          Brain’s Lymphatic System Plays Role in Migraine Pain

          Researchers discovered how the protein CGRP affects the brain's lymphatic system, contributing to migraine pain. Their study reveals that CGRP prevents cerebrospinal fluid from draining, influencing migraine attacks. This finding could lead to new therapeutic strategies for migraines. More research is needed to understand the sex differences in migraine prevalence.
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          This shows a person holding their head in pain.
          FeaturedNeurologyNeurosciencePain
          ·July 11, 2024·4 min read

          New Discovery Links Protein to Chronic Pain

          Researchers identified a new role for the PIEZO2 protein in mediating chronic pain hypersensitivity, suggesting a new target for pain relief. The study showed that mutations in PIEZO2 make pain receptors, or nociceptors, highly sensitive to mechanical stimuli, explaining persistent pain. This finding could lead to new analgesics that better address chronic pain by targeting PIEZO2 channels.
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          This shows a person in pain.
          FeaturedGeneticsNeurosciencePain
          ·June 10, 2024·7 min read

          Pruning Pain: Protein Associated with Pain Sensitivity Identified

          The protein Kif2a acts as a "gardener" for sensory neurons, regulating their axon growth. This pruning process is crucial for managing pain sensitivity. The absence of Kif2a in genetically engineered mice resulted in increased axon density and heightened pain sensitivity over time. However, a compensatory mechanism reduces pain sensitivity in the long term, offering potential insights for chronic pain management.
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          This shows an older man.
          FeaturedNeurologyNeurosciencePain
          ·May 25, 2024·3 min read

          Aging Reduces Sensitivity to Heat Pain but Not Pressure Pain

          Aging reduces sensitivity and discriminative ability for heat pain, but not pressure pain. Researchers compared pain perception in young and older adults using heat and pressure stimuli.
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          This shows a person rubbing their neck.
          FeaturedNeurologyNeurosciencePain
          ·April 22, 2024·5 min read

          Socioeconomic Factors Linked to Chronic Pain

          Socioeconomic status, lifestyle, and psychological factors significantly influence the development of chronic musculoskeletal pain after injury. The study found that individuals from lower socioeconomic backgrounds are twice as likely to experience chronic pain, and those with additional risk factors such as smoking, fear of movement, and poor support networks are up to seven times more likely.
          Read More
          This shows a woman meditating.
          FeaturedNeurologyNeurosciencePainPsychology
          ·March 12, 2024·6 min read

          AI and Mindfulness: A New Way to Manage Pain

          A new study examines the potential of artificial intelligence to shift chronic pain treatment from opioids to mindfulness-based stress reduction (MBSR). Utilizing machine learning to analyze extensive patient data, the study aims to predict which patients will benefit most from MBSR, a critical step towards personalized medicine.
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          This shows a hand.
          FeaturedNeurosciencePain
          ·February 6, 2024·5 min read

          Schwann Cells Key to Touch and Pain

          Schwann cells, previously known for their role as insulators around nerve fibers, are actively involved in detecting sensory stimuli such as touch and pain. This groundbreaking study reveals that specific types of Schwann cells form a network just beneath the skin's surface, directly connecting to nerve endings responsible for sensing mechanical pressure.
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          This shows a man and lightening.
          FeaturedNeurosciencePain
          ·January 4, 2024·5 min read

          Electrical Stimulation Enhances Hypnotizability

          Researchers have found that targeted electrical stimulation of the brain can temporarily increase a person's hypnotizability, potentially allowing more individuals to benefit from hypnosis-based therapies for pain relief and other conditions. In a study involving participants with fibromyalgia, electrical stimulation delivered to the left dorsolateral prefrontal cortex boosted hypnotizability for about an hour.
          Read More
          This shows a man in pain.
          FeaturedNeurosciencePain
          ·November 15, 2023·3 min read

          Men Feel Less Pain When It’s Inflicted By A Woman

          Researchers have uncovered a unique aspect of pain perception: men feel less pain when it is inflicted by a woman compared to a man. This phenomenon was observed in both experimental settings with healthy volunteers and postoperative patients.
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          This shows a woman covering her face.
          FeaturedNeurosciencePainPsychology
          ·November 10, 2023·5 min read

          Aching for Accord: Pain Influences Politics

          Research reveals an unusual correlation between pain sensitivity and political openness. Pain-sensitive individuals tend to endorse values and show support for politicians typically associated with the opposing political camp.
          Read More
          This shows a man listening to music.
          FeaturedNeurologyNeuroscienceOpen Neuroscience ArticlesPain
          ·October 26, 2023·5 min read

          Your Favorite Song Might Just Be Your Pain’s Worst Enemy

          Researchers discovered that music, specifically individuals' favorite tracks, can reduce pain perception. In the study, participants felt less pain intensity and unpleasantness when listening to their favorite music compared to unfamiliar relaxing tunes or silence.
          Read More
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          This shows a brain.

          Blurry Beginnings Shape Brain’s Visual Pathways

          This shows the hippocampus.

          Human Brains Keep Making Memory Neurons in Adulthood

          This shows an ear.

          Gene Therapy Restores Hearing in Those with Deafness

          This shows a brain.

          Forever Chemicals May Disrupt Brain Development

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