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Tau

This shows the difference between a healthy brain and one of an alzheimer's patient.

Featured Neurology

·February 25, 2014·2 min read

Brain Cell Activity Regulates Alzheimer’s Protein

A new study reports that increased neural activity boosts tau levels in the brain.

This is a sagittal MRI slice with highlighting indicating location of the posterior cingulate.

Featured Neurology

·August 19, 2013·3 min read

Brain Network Decay Detected in Early Alzheimer’s

Disruptions in brain networks emerge around the same time as chemical markers for Alzheimer's disease appear in spinal fluid, new research suggests.

Three panels show tangles and Lewy bodies.

Featured Neurology

·July 3, 2013·4 min read

Shape-shifting Disease Proteins May Explain Variable Appearance of Neurodegenerative Diseases

Researchers discover alpha-synuclein proteins can morph into different strains. This can promote misfolding of other disease proteins associated with neurodegenerative diseases.

The image shows neurofibrillary tangles associated with Alzheimer's.

Featured Neurology

·June 26, 2013·3 min read

Alzheimer’s Disease Mouse Models Point To A Potential Therapeutic Approach

Using well known mouse models, researchers demonstrate a potential new target to fight Alzheimer's and other neurodegenerative diseases.

The image shows the tau proteins associated with Alzheimer's disease.

Featured Neurology

·June 19, 2013·3 min read

New Alzheimer’s Research Suggests Possible Cause: The Interaction of Proteins in the Brain

Researchers discover by looking at amyloid-beta and tau independently that the interaction between the proteins could be the key to the cognitive decline associated with Alzheimer's disease. As the interaction between the two proteins increased, the progression of Alzheimer's worsened.

The image shows a brain scan of a person with TBI.

Featured Neurology

·May 29, 2013·3 min read

From Trauma to Tau

Researchers discover traumatic brain injuries generate tau oligomers, a protein associated with Alzheimer's and other neurodegenerative diseases. The discovery could provide insight into lasting brain damage caused by TBI.

Featured Neuroscience

·May 23, 2013·4 min read

Scientists Discover Cinnamon Compounds’ Potential Ability to Prevent Alzheimer’s Disease

Cinnamaldehyde and epicatechin, two compounds found in cinnamon, are showing promise in the fight against Alzheimer's disease.

The image shows a PET scan of a brain of a person with Alzheimer's disease.

Featured Neuroscience

·February 15, 2013·2 min read

Neuronal Activity Induces Tau Release from Healthy Neurons

Researchers discover neuronal activity can stimulate tau release from healthy neurons in the absence of cell death. The study shows treatment of neurons with known biological signaling molecules increases the release of tau into the culture medium.

Image shows brain slices with deposits of proteins associated with Alzheimer's and Parkinson's disease.

Featured Neurology

·February 5, 2013·3 min read

Study Confirms No Transmission of Alzheimer’s Proteins Between Humans

While evidence suggests pathological proteins linked to the onset and progression of neurodegenerative disorders are capable of spreading from cell-to-cell within the brains of affected individuals, new research shows no evidence to support concerns that these abnormal disease proteins are “infectious” or transmitted from animals to humans or from one person to another.

Neurology Neuroscience Business

·July 19, 2012·2 min read

Anti-Tau Drug Improves Cognition, Decreases Tau Tangles in Alzheimer’s Disease Models

Penn Medicine research presented today at the 2012 Alzheimer's Association International Conference shows that an anti-tau treatment called epithilone D (EpoD) was effective in preventing and intervening the progress of Alzheimer's disease in animal models, improving neuron function and cognition, as well as decreasing tau pathology.