Researchers identify a driving network for compulsivity in those with alcohol use disorders. The study reports heavy drinkers have more activity in the prefronal cortex, insular and striatum, areas of the brain critical for reward and decision making.
A new study reveals people with schizophrenia have a disrupted stress response. Researchers report those with schizophrenia have an increase in dopamine release in the striatum, but not in the prefrontal cortex, in response to stress.
Researchers say melanocortin 4 receptors may play a role in unease and reward. The study reports dopamine levels fell in the reward system of mice when the animal experienced something unpleasant. However, in mice lacking the melanocortin 4 receptor, dopamine levels increased slightly following a negative experience.
According to a new study, nicotine reduces dorsal striatal output, underlying the urge to smoke and making it difficult to quite the addiction.
Researchers have identified a reduced exchange of glutamine between astrocytes and neurons in a new Huntington's disease study.
A family with a rare genetic mutation are helping researchers answer important questions about how the human brain is wired. The family, who share an altered copy of the DCC gene, have less connectivity between areas where dopamine neurons originate and their target sites.
A new study reports foods that contain both carbs and fats evoke greater response in the brain's reward center than foods that contain either just carbs or fats.
A new study reports people who have a family history of alcohol use disorder release more dopamine in the ventral striatum as a response to the expectation of receiving an alcoholic drink than those without a family history of alcoholism.