Researchers have pinpointed how brain activity changes in mouse models of Parkinson's disease, providing clues as to what may drive symptoms of the disease in humans. Read More
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Researchers report the striatum and amygdala are less able to track changes in threat levels in those with severe PTSD. The findings may serve as a biomarker to evaluate who may be at greater risk of PTSD symptoms. Read More
Researchers have made a surprise discovery that could help provide treatment options for a range of conditions from Parkinson's disease to depression. Researching how to transform supportive brain cells into neurons, the scientists unexpectedly transformed mature inhibitory striatal neurons into dopamine producing neurons. Read More
A new brain imaging study reveals how the midbrain and striatum, two key areas of the dopamine system, become more active when a person updates their beliefs about the world around them. Read More
A new study reveals why, when the brain is faced with an overwhelming number of similar options, it struggles to make a decision. Read More
Researchers report exercise can promote adult hippocampal neurogenesis and improve cognition in mouse models of Alzheimer's disease. The study identifies ways to mimic the beneficial effects of experience through pharmacological and gene therapy. Read More
According to a new study those with higher criminal tendencies choose to take risks and gamble more than law abiding citizens. Read More
Researchers identify a driving network for compulsivity in those with alcohol use disorders. The study reports heavy drinkers have more activity in the prefronal cortex, insular and striatum, areas of the brain critical for reward and decision making. Read More
Researchers shed light on the role the caudate nucleus plays in pessimism. The study reports stimulating this area of the brain generates a negative outlook that clouds decision making. Read More
Researchers report the brain's response to taste stimuli is linked to higher anxiety and a drive for thinness in those with anorexia. Read More
A new study reveals people with schizophrenia have a disrupted stress response. Researchers report those with schizophrenia have an increase in dopamine release in the striatum, but not in the prefrontal cortex, in response to stress. Read More
Researchers say melanocortin 4 receptors may play a role in unease and reward. The study reports dopamine levels fell in the reward system of mice when the animal experienced something unpleasant. However, in mice lacking the melanocortin 4 receptor, dopamine levels increased slightly following a negative experience. Read More
