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          striatum

          This shows an astrocyte
          FeaturedNeurosciencePsychology
          ·April 12, 2023·5 min read

          The Brain’s Support Cells May Play a Key Role in OCD

          A newly discovered cellular mechanism that involves astrocytes, as well as neurons, appears to be involved in repetitive behaviors and OCD.
          Read More
          This shows the outline of a head
          FeaturedNeuroscienceOpen Neuroscience Articles
          ·February 21, 2023·4 min read

          Brain Circuit Involved in Fentanyl Abuse and Relapse Identified

          Fentanyl enhances direct pathway medium spiny neurons activity in the striatum. During withdrawal from the opioid, inhibitory signals from direct pathway medium spiny neurons to dopaminergic neurons become enhanced. The enhanced suppression of dopaminergic neurons contributes to the negative emotions associated with fentanyl withdrawal. Inhibiting the direct pathway medium spiny neurons can reduce withdrawal symptoms and associated anxiety behaviors.
          Read More
          This shows a brain
          FeaturedNeurosciencePsychology
          ·February 7, 2023·5 min read

          Differences in Dopamine Signals in Patients With History of Alcohol Use Disorder

          The connection between dopamine and counterfactual information, or notions of relief and regret, is altered in those with alcohol use disorder.
          Read More
          This shows neurons
          FeaturedNeurologyNeuroscience
          ·January 20, 2023·6 min read

          How Huntington’s Disease Affects Different Neurons

          Researchers have identified how two different populations of neurons in the striatum are affected differently in Huntington's disease. The neurodegeneration of one of these populations leads to motor defects while damage to the other population located in striosomes may account for mood disorders associated with the early stages of Huntington's.
          Read More
          This shows a head made of cogwheels
          FeaturedNeuroscience
          ·November 30, 2022·4 min read

          A Crucial Role of Brain’s Striatum Cilia in Time Perception

          Destruction or removal of the cilia in the striatum impairs time perception and judgment, new research suggests. The findings could have implications for a range of diseases including schizophrenia, ASD, and Parkinson's.
          Read More
          This shows a model of a head and a brain
          FeaturedNeuroscienceOpen Neuroscience Articles
          ·August 25, 2022·4 min read

          Investigating the Role of Dopamine Circuits in Habit Formation

          Dopamine neurons connect subregions of the striatum that contribute to habit formation. The findings shed new light on how habits are formed, and how they can be broken.
          Read More
          This shows a diagram from the study
          FeaturedNeuroscience
          ·July 18, 2022·7 min read

          Observing Memory Formation in Real Time

          Study reveals how motor memories are formed and how they remain persistent. The findings may help illuminate the root cause of motor disorders like Parkinson's disease.
          Read More
          This shows diagrams from the study
          FeaturedNeuroscienceOpen Neuroscience Articles
          ·May 26, 2022·3 min read

          Synaptic Connectivity of a Novel Cell Population in the Striatum

          Researchers characterize a novel neural population within the striatum that appears to be responsible for the interplay between acetylcholine and GABA.
          Read More
          This shows the outline of two heads
          FeaturedNeurosciencePsychology
          ·May 10, 2022·6 min read

          Psychopaths Are More Likely to Have a Larger Striatum

          Neuroimaging study reveals those with psychopathy have a 10% larger striatum than non-psychopaths. Researchers say the increased size of the striatum, a brain area associated with cognitive and social functions, may account for a higher likelihood of impulsive behaviors and increased need for stimulation often associated with psychopathy. Additionally, researchers suggest there may be an element of heredity in the neural anatomy, adding support to the neurodevelopmental perspective of psychopathy.
          Read More
          This shows striosomes
          FeaturedNeuroscienceOpen Neuroscience Articles
          ·March 25, 2022·6 min read

          Neurons That Encode the Outcomes of Actions

          Striosomes, a collection of neurons in the brain's striatum, help with decision-making that requires the evaluation of risks and benefits.
          Read More
          This shows a diagram from the study
          AutismFeaturedGeneticsNeuroscience
          ·February 28, 2022·6 min read

          Familiar Objects Can Prevent Autism-Like Behaviors in Mouse Model

          Exposing mice with the autism-associated SHANK3 genetic mutation to new environments can trigger autism-like behaviors, including repetitive movements and problems with social engagement. However, adding familiar objects to the novel environment during the first exposure can reduce the behavioral and brain signaling deficits.
          Read More
          This shows a brain
          FeaturedNeuroscienceOpen Neuroscience Articles
          ·February 7, 2022·3 min read

          A Yet Unknown Neural Mechanism of Habit Formation Identified

          Study provides insight into the behavioral function of dopamine signaling in the striatum.
          Read More
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          This shows a fruit fly.

          Researchers Release The Most Detailed Fruit Fly Nerve Cord Connectome

          This shows a woman in VR surrounded by roses.

          Wireless Olfactory Feedback System Enhances VR Experiences

          This shows a sad little girl.

          Alexithymia & Childhood Trauma: Unraveling The Mysterious Connection

          This shows a head.

          Deciphering the Century-Old Mystery: Revealing the Temporal Pole’s Function in the Brain

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