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Featured Neurology Neuroscience Open Neuroscience Articles

·May 13, 2020·3 min read

Significant differences exist among neurons expressing dopamine receptors

Dopamine receptors have different molecular features and functions depending on their anatomical location within the striatum. The findings could help develop better-targeted treatments for a range of disorders from schizophrenia to Parkinson's disease.

Featured Genetics Neuroscience

·September 15, 2020·3 min read

Reward and Punishment Take Similar Paths in the Mouse Brain

Researchers found specific neurons in the striosome that help mice learn to avoid negative experiences.

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Featured Open Neuroscience Articles Psychology

·May 29, 2014·4 min read

Creatures of Habit

A new study reports people affected by substance abuse, eating disorders and OCD share a common pattern of decision making and similarities in brain structure.

Featured Neuroscience Psychology

·January 22, 2019·3 min read

Brain Biomarkers Identify Those at Risk of Severe PTSD Symptoms

Researchers report the striatum and amygdala are less able to track changes in threat levels in those with severe PTSD. The findings may serve as a biomarker to evaluate who may be at greater risk of PTSD symptoms.

Electrophysiology Featured Neuroscience Open Neuroscience Articles

·October 12, 2020·5 min read

Dopamine and Serotonin Play a Role in Human Perception and Decision-Making

Researchers recorded alterations in levels of both dopamine and serotonin in the brain when people perform perception and decision making based tasks.

Featured Neuroscience Open Neuroscience Articles

·December 27, 2019·3 min read

A molecular map of the brain’s decision-making area

Using RNA sequencing, researchers have created a spatiomolecular map of the striatum, an area of the brain implicated in decision making and addiction.

Featured Open Neuroscience Articles Psychology

·September 19, 2017·4 min read

Behavioral Therapy Increases Connectivity in Brains of People with OCD

A neuroimaging study reveals people with OCD who receive daily cognitive behavioral therapy to help curb their compulsive behaviors show stronger connections between specific brain regions.

Autism Featured Genetics Neuroscience

·February 28, 2022·6 min read

Familiar Objects Can Prevent Autism-Like Behaviors in Mouse Model

Exposing mice with the autism-associated SHANK3 genetic mutation to new environments can trigger autism-like behaviors, including repetitive movements and problems with social engagement. However, adding familiar objects to the novel environment during the first exposure can reduce the behavioral and brain signaling deficits.

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Featured Neuroscience

·August 19, 2015·6 min read

Creatures of Habit: How Neurons Weigh Behavioral Cost and Reward

According to a new study, habit formation is driven by neurons in the striatum which represent both the cost and reward of the behavior.

Featured Neuroscience Open Neuroscience Articles

·May 26, 2022·3 min read

Synaptic Connectivity of a Novel Cell Population in the Striatum

Researchers characterize a novel neural population within the striatum that appears to be responsible for the interplay between acetylcholine and GABA.

Featured Genetics Neuroscience Open Neuroscience Articles

·December 21, 2017·5 min read

How Genes Influence Performance of Sleep Deprived People

People with a variation of the DRD2 gene are more resilient to the effects of sleep deprivation when completing tasks that require cognitive flexibility, a new study reports.