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SSRIs

·March 6, 2022·3 min read

Pregnant Women Have Lingering Depression Despite Antidepressant Treatment

Many women experienced lingering depression throughout pregnancy and postpartum, despite using SSRI antidepressants, a new study reports.

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·November 27, 2021·5 min read

Looking to Mitochondria for Clues About Depression

People with untreated depression have lower levels of mitochondrial proteins. For those who responded to the SSRI antidepressants, the proteins returned to a normal level, but showed no increase in those who did not respond to medication.

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·November 15, 2021·4 min read

COVID Patients on SSRI Antidepressants Are Less Likely to Die

A comparison of medical records reveals people who took SSRI antidepressants, specifically fluoxetine (Prozac), were less likely to die of COVID-19 than a matched control group. The findings add to a growing body of evidence that SSRIs may have beneficial effects against the worst symptoms of coronavirus.

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·November 8, 2021·4 min read

Expectations and Dopamine Can Affect Outcome of SSRI Antidepressant Treatment

The placebo effect combined with dopamine levels can determine whether symptoms of depression and social anxiety will improve in patients prescribed SSRI antidepressants. Researchers found the positive effect of the medications was four times higher in patients with high expectations the treatment would work compared to those with lower expectations.

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·August 23, 2021·5 min read

Prozac Changes Fat Composition of the Brain

Prozac reduced polyunsaturated fatty acid lipid concentrations in the brains of juvenile macaque monkeys.

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·August 17, 2021·4 min read

Histamine and Inflammation Could Be Key Players in Depression

A new study adds to the growing body of research linking inflammation to depression. Researchers found the molecule histamine directly inhibits the release of serotonin in the brain by attaching to inhibitory receptors on serotonin neurons in mice.

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·June 24, 2021·4 min read

Antidepressants Safe During Pregnancy

Taking SSRI antidepressants does not increase the risk of developmental delays or autism in children, a new study reports. However, there is an increased risk for ASD and developmental delays in children whose mothers suffer from maternal psychiatric disorders.

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·June 1, 2021·6 min read

Protecting the Intellectual Abilities of People at Risk for Psychosis

Prescribing SSRIs during late childhood to those with genetic risk factors for psychosis can reduce the deterioration of intellectual abilities, a new study reveals. SSRIs appear to have a neuroprotective effect for certain brain areas associated with the onset of psychosis if provided early.

This shows a depressed looking young man

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·February 18, 2021·4 min read

New Information on the Effects of Antidepressants

SSRI's, ketamine, and tricyclic antidepressants all bind with TrkB. The findings challenge the roles serotonin and glutamate receptors play in the effects of antidepressant medications.

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·December 28, 2020·4 min read

New Antidepressants Can Lift Depression and Suicidal Thoughts Fast, but Don’t Expect Magic Cures

With the risk of potential for abuse, some new fast-acting antidepressants, like Ketamine, may not be a magic "cure-all" for depression.

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·August 14, 2020·6 min read

Study Uncovers the Molecular Events by Which Popular Antidepressants Work

Activity of the c-Fos gene begins the increase on the ninth day of exposure to antidepressants. By day 14, mice showed behavioral changes associated with SSRI use. This may explain why suicide rates drop after nine days of treatment, and symptoms of depression improve after three weeks.

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·June 14, 2020·2 min read

Clozapine may cause obsessions and compulsions

The antipsychotic medication clozapine can trigger severe obsessive-compulsive symptoms (OCS) in patients. Adding aripiprazole can help manage clozapine-associated OCS.