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SSRIs

Featured Open Neuroscience Articles Psychology

·August 14, 2020·6 min read

Study Uncovers the Molecular Events by Which Popular Antidepressants Work

Activity of the c-Fos gene begins the increase on the ninth day of exposure to antidepressants. By day 14, mice showed behavioral changes associated with SSRI use. This may explain why suicide rates drop after nine days of treatment, and symptoms of depression improve after three weeks.

Featured Neuroscience Psychology

·June 14, 2020·2 min read

Clozapine may cause obsessions and compulsions

The antipsychotic medication clozapine can trigger severe obsessive-compulsive symptoms (OCS) in patients. Adding aripiprazole can help manage clozapine-associated OCS.

Featured Neuroscience Open Neuroscience Articles Psychology

·May 15, 2020·5 min read

Countering the negative effects of a common antidepressant

The SSRI sertraline (Zoloft), if taken while pregnant, can result in birth defects caused by the drug damaging a cell's genetic information. Researchers report one potential way to counter the effect is with specific antioxidants.

This shows a print out of the genetic findings from different brain regions

Featured Genetics Neuroscience Psychology

·May 11, 2020·1 min read

Why some people are more prone to anxiety

Increased levels of serotonin transporters in the amygdala may explain why some people are more prone to anxiety than others.

Featured Neuroscience Psychology

·April 29, 2020·4 min read

Increased risk of language and cognition deficits in children whose mothers took SSRI antidepressants during pregnancy

Children exposed to SSRI antidepressants in utero had an increased risk of experiencing language and cognitive deficits in kindergarten.

Featured Neuroscience Psychology

·March 14, 2020·5 min read

How chronic stress changes the brain, and what you can do to reverse the damage

Chronic stress can affect a person's health and mental well being. Due to the COVID-19 virus, chronic stress is on the rise worldwide. Researchers examine the general and psychological health implications of chronic stress and suggest some methods we can adopt to keep our stress levels in check.

Featured Neuroscience Open Neuroscience Articles Psychology

·February 21, 2020·5 min read

Antidepressant harms baby neurons in lab-grown ‘mini-brains’

Using a mini-brain model, researchers report the popular SSRI antidepressant Paroxetine can induce brain cell developmental abnormalities that could lead to adverse effects in children.

This shows a man looking out of a window

Featured Neuroscience Open Neuroscience Articles Psychology

·February 20, 2020·3 min read

Extended antidepressant use creates physical dependence

Long-term use of antidepressants can create physical dependence and severe withdrawal symptoms for patients looking to stop their treatment. Patients who quit their medication often experience Antidepressant Discontinuation Syndrome, which results in flu-like symptoms, insomnia, nausea, and other symptoms associated with withdrawal.

This is a drawing of a brain and brain waves

Featured Neuroscience Psychology

·February 10, 2020·5 min read

Neural signature identifies people likely to respond to antidepressant medication

A new machine-learning algorithm that analyzes EEG data can identify reliable and robust neural signatures associated with antidepressant treatment response.

Featured Neuroscience Psychology

·January 8, 2020·5 min read

Are some antidepressants less risky for pregnant women?

Alteration of placental serotonin levels due to maternal depression or antidepressant use may be associated with the disruption of placental estrogen production.