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SSRIs

·September 25, 2019·5 min read

AI helps scientists predict depression outcomes

Artificial intelligence technology was able to identify specific brain regions which were most important for predicting whether a person with depression would respond to SSRI antidepressants.

Featured Neuroscience Open Neuroscience Articles Psychology

·September 20, 2019·6 min read

Common antidepressant may not reduce depression symptoms, but does reduce anxiety

Sertraline (Zoloft), a commonly prescribed SSRI antidepressant, may not be as effective at treating depression within 6 weeks as previously thought. However, the drug is effective for treating anxiety symptoms.

Featured Neuroscience Psychology

·September 6, 2019·5 min read

How serotonin and a popular anti-depressant affect the gut’s microbiota

Serotonin and SSRIs like Prozac can have a major effect on gut bacteria. When exposed to serotonin, specific gut bacteria grew to higher levels. However, when exposed to SSRIs, the bacterium grew to much lower levels in mouse models.

Featured Neuroscience Psychology

·September 1, 2019·5 min read

Psychedelic drugs: would you accept a prescription? It depends if you’ve tried them before

Numerous studies have linked controlled psychedelics to improvements in mental health conditions such as depression and PTSD. In March, the FDA approved Esketamine as a treatment for depression. However, with much stigma surrounding psychedelics, researchers question how many patients would take psychedelic medications if prescribed to them. According to a new study, 40% of people with no experience of psychedelics would be unlikely to take the prescription due to fears of 'brain damage' or a 'bad trip'.

Featured Neuroscience Psychology

·July 10, 2019·2 min read

How a popular antidepressant drug could rewire the brain

Fluoxetine rearranges nerve fibers in the hippocampus of mice, a new study reports.

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Featured Neurology Neuroscience Open Neuroscience Articles Psychology

·June 25, 2019·4 min read

Common antidepressants interact with opioid med to lessen pain relief

SSRI antidepressants, such as Prozac and Paxil, interact with opioid medications to make them less effective at providing relief from chronic pain. Tramadol relies on activation of the CYP2D6 enzyme to control pain, but SSRIs inhibit this enzyme. Researchers suggest prescribing different classes of antidepressants which do not suppress the enzyme may benefit those in need of opioid medications. Alternatively, non-opioid pain killers should be considered for those who can not switch from SSRIs.

Featured Genetics Neuroscience Psychology

·May 22, 2019·3 min read

New therapeutic target for depression identified

A fragment of the neuropeptide Galanin appears to play a role in anhedonia in mouse models of depression. Galanin could be a potential target for the treatment of depression.

Autism Featured Neuroscience Open Neuroscience Articles Psychology

·April 30, 2019·4 min read

Possible link between autism and antidepressants use during pregnancy: Mouse Study

A new study in mice reveals a possible link between the use of SSRI antidepressants during pregnancy and an increased risk of autism-like symptoms in offspring. Offspring exposed to fluoxetine (Prozac) in utero were more likely to exhibit impaired neurotransmission caused by an overactive serotonin receptor in the prefrontal cortex, an area of the brain implicated in modulating social behaviors. However, treating the mice with a compound that blocks the receptor alleviated the behavioral problems and improved working memory.

Featured Neuroscience

·April 18, 2019·5 min read

Fish are accumulating certain antidepressants, antibiotics and sun cream components

Antidepressants, such as the SSRI amitriptyline, antibiotics associated with developmental problems and sun cream components are contaminating water, and are being accumulated in fish. Exposure to the medications has effects on the molecular level to the fish. Researchers say this poses a problem as consumption of gilt-head bream is on the rise, and there could be a risk of the contaminants reaching humans via diet.

Featured Genetics Neuroscience Psychology

·March 22, 2019·4 min read

When neurons are out of shape, antidepressants may not work

Differences in serotonergic neuron morphology, along with altered gene expression have been identified in patients with MDD. The findings shed light on why some patients do not respond to SSRI antidepressants.

Featured Neurology Neuroscience Open Neuroscience Articles

·March 20, 2019·7 min read

New study reshapes understanding of how the brain recovers from injury

Retinal ganglion cell survival following a stroke depends on whether the pathway to the primary visual area remains active. Cells connected to inactive areas of the visual cortex suffer atrophy and degenerate, leading to permanent visual impairment.

Featured Neuroscience Psychology

·February 1, 2019·4 min read

Hyperactive Neurons May Be to Blame When Antidepressants Don’t Work

Researchers shed new light on why some people may not respond to antidepressants for major depressive disorder. The study reports, neurons in the brains of some with MDD may become hyperactive in the presence of SSRIs.

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SSRIs

AI helps scientists predict depression outcomes

Common antidepressant may not reduce depression symptoms, but does reduce anxiety

How serotonin and a popular anti-depressant affect the gut’s microbiota

Psychedelic drugs: would you accept a prescription? It depends if you’ve tried them before

How a popular antidepressant drug could rewire the brain

Common antidepressants interact with opioid med to lessen pain relief

New therapeutic target for depression identified

Possible link between autism and antidepressants use during pregnancy: Mouse Study

Fish are accumulating certain antidepressants, antibiotics and sun cream components

When neurons are out of shape, antidepressants may not work

New study reshapes understanding of how the brain recovers from injury

Hyperactive Neurons May Be to Blame When Antidepressants Don’t Work

How Scientists Cracked the Ketamine Code for Depression

Brain Prioritizes “Sound Offsets” During Hearing Repair

Glucose Levels Signal the Growth of Myelin

Why Your Brain “Dreams” Even When You’re Awake

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