Researchers report transplanting altered neural stem cells into the brains of mice genetically engineered to exhibit symptoms of ALS, delayed the progression of the disease and extended lifespan.
Researchers report the formation of larger, more visible SOD1 aggregates may help to protect brain cells.
UC Berkeley researchers report they have successfully used CRISPR-Cas9 gene editing to delay symptoms and extend lifespan in mouse models of ALS.
Researchers have generated motor neurons from people with familial ALS who carry FUS mutations.
According to researchers, a drug that has been used for decades to help treat malaria can lower levels of a biomarker associated with ALS.
Study implicates abnormalities in SOD1 with Parkinson's disease and ALS.
A new study reports an antidepressant temporarily inhibits the blood-brain barrier, allowing drugs to enter the brain. The findings could have implications for treating neurological diseases from ALS to epilepsy.
Researchers have identified a naturally occurring molecule that has the potential for preserving sites of communication between nerves and muscles in ALS.
Researchers report a collapse of the mitochondria-associated membrane is a common halmark in two genetic forms of ALS.
A new study reports oligodendrocytes induce motor neuron death in ALS.
A new study reveals stabilizing the SOD1 protein can help reverse protein clumping in neurons affected by ALS.
Researchers have identified a modifier gene that affects the risk of developing degenerative myelopathy, a canine disease similar to ALS in Welsh corgis.
