By increasing the signaling activity of a protein called muscle skeletal receptor tyrosine-protein kinase (MuSK), researchers were able to keep nerve cells attached to muscle longer into the progression of the disease in a mouse model of ALS.
A new treatment for ALS, which uses a technique that turns off the mutated SOD1 gene, has passed an early phase clinical trial for safety.
A new study finds slowdowns in the transport and delivery of proteins, nutrients and signaling molecules within nerve cells could contribute to the development of ALS.
By reducing the expression of the SOD1 gene, ALS onset and progression is slowed, a new study suggests.
New research could help find a solution to slowing down the progression of motor neuron disease.
Researchers discover ALS is transmitted from cell to cell, suggesting the spread of the disease could be blocked.
Researchers pinpoint an error in protein formation which could be the root of ALS.
Researchers discover a recently approved epilepsy medication could also help to treat ALS.
Researchers discover Alzheimer's disease, and other neurodegenerative conditions could be linked to prion-like proteins.
A new study suggest specific protein instability as a cause of ALS.
Researchers use techniques which illuminates subtle changes in proteins and uncover new insights into the underlying causes of ALS.
Researchers have identified a transport defect in models of familial ALS which leads to the accumulation of damaged components.
