A new drug modulates, rather than inhibits, a key enzyme implicated in the formation of Alzheimer's related plaques.
Activating group 2 innate lymphoid cells in aging brains helps improve memory in mice. The findings could help in the development of treatments for neurodegenerative diseases associated with aging.
Study reports specific gut bacteria can influence the development of Alzheimer's disease. In mouse models, long term antibiotic treatment reduced inflammation and the formation of amyloid plaques. However, the reduction was only seen in males. Additionally, the antibiotic treatment altered the activation of microglia in the male mouse models.
Researchers report sleep can help immune cells attach to targets and help fight infection. The study reveals how sleep assists the body in fighting infections, whereas conditions like chronic stress can make the body more susceptible to illness.
A new study reveals how microglia help clear dead and damaged materials away from healthy, neighboring neurons following injury.
Depleting BACE1 completely reverses the formation of amyloid plaques and improves cognitive function in mouse models of Alzheimer's disease, researchers report.
A new study in the Journal of Experimental Medicine report Zika virus could be used to target and treat glioblastoma brain cancer. Researchers found a mouse adapted strain of Zika slowed tumor growth and extended life span in mice with glioblastoma.
Researchers report Huntington's disease is not only a neurodegenerative disease, it is also a disease that affects muscle tissues.
Researchers have identified several new biological markers to measure the progression of the inherited neurodegenerative disorder Huntington's disease.