A study of marmoset monkeys reveals a genetic variation of the SLC6A4 repeat region may contribute to anxiety via neurochemical changes in brain areas associated with emotional processing.
Specific transfer RNAs (tRNAs) are associated with epilepsy. The levels of tRNA fragments in blood samples are higher pre-seizure. The findings provide a novel biomarker for the detection of seizures prior to their occurrence.
Findings from a small sample study link small intestinal bacterial overgrowth (SIBO) to restless leg syndrome.
Studying brain tissue samples from people with ASD revealed a common set of alterations in genes associated with synaptic communication between neurons. The changes were identified mainly in neurons in the uppermost layers of the neocortex.
Genetic mutations which lead to abnormal RNA in regions of repeat DNA sequences set off anti-viral like inflammatory responses. This leads to apoptosis and ultimately trigger the onset of neurodegenerative diseases.
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Axon myelination is significantly disrupted in patients with Alzheimer's disease. Researchers also found brain cells of men and women vary significantly in how their genes respond to the neurodegenerative disease.
Researchers discovered changes in thousands of genes induced by the tumor microenvironment. The study may help in identifying new biomarkers for the early detection, and subsequent treatment, of brain cancers.