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RNA

Featured Genetics Neuroscience Psychology

·April 22, 2020·4 min read

Novel class of specific RNAs may explain increased depression susceptibility in females

Long non-coding RNAs (lncRNAs) are significantly altered in depression in both sex and brain site-specific manners. The LINC00473 gene is downregulated in the prefrontal cortex of depressed females, but not males. Findings reveal the role of LINC00473 in sex-specific depression and may explain why females are more vulnerable to depressive symptoms than males.

Featured Neuroscience

·April 13, 2020·4 min read

Remdesivir effective against a key enzyme of coronavirus that causes COVID-19

Remdesivir, a drug initially developed to fight Ebola and currently being fast-tracked into trials for COVID-19, is highly effective at stopping the replication mechanism of coronavirus. The drug tricks the virus by mimicking its building blocks, causing the inhibitor to get incorporated repeatedly, and preventing replication of SARS-CoV-2.

Featured Genetics Neuroscience

·April 9, 2020·4 min read

COVID-19: SARS-CoV-2 mapped out

Newly discovered modifications of the coronavirus RNA offers clues for combatting COVID-19. The findings also shed light on the lifecycle of the SARS-CoV-2 virus.

Autism Featured Genetics Neuroscience Open Neuroscience Articles Psychology

·April 8, 2020·3 min read

Genes sow seeds of neuropsychiatric diseases before birth and in early childhood

Researchers identify genetic variations in the prefrontal cortex during different stages of development to assess how psychiatric conditions, such as autism and schizophrenia, may arise in individuals.

Featured Neuroscience

·April 1, 2020·4 min read

Antiviral used to treat cat coronavirus could hold key to COVID-19

A drug used to treat feline infectious peritonitis, an often fatal coronavirus infection in cats, may hold the key for developing a treatment for human COVID-19.

Featured Neuroscience Open Neuroscience Articles

·March 20, 2020·4 min read

New drug target found for COVID-19

Researchers have identified a potential new drug target for COVID-19. The scientists mapped the anatomical structures of two critical SARS-CoV-2 proteins in the nsp10/nsp16 complex. If a drug can be developed to inhibit nsp10/nsp16, researchers believe the immune system should be able to detect the infection and eradicate it faster.

Featured Neuroscience

·March 10, 2020·3 min read

Neuron ‘nursery’ in nose tissue could help correct smell loss

The olfactory epithelium may be a hub for neurogenesis.

Featured Genetics Neuroscience

·March 4, 2020·4 min read

Researchers catalog dozens of mutations in crucial brain development gene

Researchers have identified 107 mutations in the RNA helicase DDX3X that cause cortical malformations in the developing brain. As the DDX3X gene is carried by the X chromosome, the associated developmental problems are more likely to occur in females. In severe cases, the functional changes in DDX3X resulted in a smaller or missing corpus callosum. Almost all of the mutations occurred de novo, meaning they happened during early development rather than being inherited from a parent. Researchers say the malfunction can now be considered to be a development disability syndrome.

Featured Neuroscience

·October 24, 2019·5 min read

Gut instincts: Researchers discover first clues on how gut health influences brain health

Mice bred to be germ-free, and those treated with antibiotics showed a significant reduction in the ability to learn that a threatening danger was no longer present. Sequencing the RNA of microglia in the brains of the animals reveals altered gene expression in the immune cells, which play a role in remodeling how neurons connect during the learning process. Restoring the gut microbiota reverse the learning problems.

Featured Genetics Neuroscience

·August 26, 2019·3 min read

Scientists have found longevity biomarkers

Exploring the effects of 17 different lifespan-extending interventions on gene activity, researchers identified genetic biomarkers for longevity in mice.

This shows a researchers holding a brain slice

Featured Genetics Neuroscience

·August 25, 2019·6 min read

Highest-resolution human brain ‘parts list’ to date lays road map to better treatments

Researchers have created the most comprehensive 'parts list' of the human brain to date. They uncovered crucial differences between human and mouse brain cells. The findings may explain why many drugs used in research do not work in human models.

Featured Genetics Neuroscience Psychology

·August 22, 2019·3 min read

Stress in pregnancy impacts childrens’ vulnerability to stress in adulthood

Prenatal stress can have an epigenetic impact on the future mental health of offspring. Adult children of women who experienced prenatal stress are more vulnerable to stress and other mental health disorders.

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RNA

Novel class of specific RNAs may explain increased depression susceptibility in females

Remdesivir effective against a key enzyme of coronavirus that causes COVID-19

COVID-19: SARS-CoV-2 mapped out

Genes sow seeds of neuropsychiatric diseases before birth and in early childhood

Antiviral used to treat cat coronavirus could hold key to COVID-19

New drug target found for COVID-19

Neuron ‘nursery’ in nose tissue could help correct smell loss

Researchers catalog dozens of mutations in crucial brain development gene

Gut instincts: Researchers discover first clues on how gut health influences brain health

Scientists have found longevity biomarkers

Highest-resolution human brain ‘parts list’ to date lays road map to better treatments

Stress in pregnancy impacts childrens’ vulnerability to stress in adulthood

Gene Therapy Restores Hearing in Those with Deafness

Forever Chemicals May Disrupt Brain Development

Kids Outsmart AI in Puzzle Game That Builds Critical Thinking

Drug-Coated Neural Implants Reduce Immune Rejection

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