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psychopharmacology

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·April 6, 2021·4 min read

Resurging Psychedelic Therapies for Depression

As interest in using psychedelics to treat a range of mental health disorders grows, researchers consider the impact and therapeutic benefits of using psychedelics to help alleviate symptoms of depression.

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·March 3, 2021·6 min read

Researchers Identify Brain Ion Channel as New Approach to Treating Depression

Ezogabine, a drug that opens up the KCNQ2/3 type potassium channel, significantly improved symptoms of depression and anhedonia.

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·February 21, 2021·4 min read

From Trippy Drugs to Therapeutic Aids – How Psychedelics Got Their Groove Back

From microdosing to improve cognition, to treating a range of mental health disorders, researchers evaluate the rise in the use of psychedelics and their potential as medicines.

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·February 18, 2021·4 min read

New Information on the Effects of Antidepressants

SSRI's, ketamine, and tricyclic antidepressants all bind with TrkB. The findings challenge the roles serotonin and glutamate receptors play in the effects of antidepressant medications.

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·January 30, 2021·4 min read

Why Do Psychiatric Drugs Help Some, but Not Others?

Study reveals the function of a specific protein works differently in the brains of men and women. The findings help explain why some psychiatric disorders and resistance to treatments vary between the sexes.

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·January 26, 2021·5 min read

LSD May Offer Viable Treatment for Certain Mental Disorders

LSD increases social behaviors by activating 5-HTPA serotonin receptors and AMPA receptors in the prefrontal cortex, and the mTORC1 protein. Activating all three factors promoted social interactions. The findings suggest supervised LSD microdosing may help alleviate some of the social problems associated with ASD and other mental health disorders that impact social behaviors.

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·January 5, 2021·5 min read

New Clues Why Gold Standard Treatment for Bipolar Disorder Doesn’t Work for Majority of Patients

Decreased activation of the LEF1 gene is more common in bipolar patients who do not respond to lithium.

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·January 3, 2021·4 min read

A First Look at How the Psychedelic Salvinorin A Works in the Brain

As with other psychedelics, salvinorin A increased activity across the brain. However, salvinorin A use resulted in more random and disconnected signaling in the default mode network, a brain network associated with relaxing and daydreaming.

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·December 28, 2020·4 min read

New Antidepressants Can Lift Depression and Suicidal Thoughts Fast, but Don’t Expect Magic Cures

With the risk of potential for abuse, some new fast-acting antidepressants, like Ketamine, may not be a magic "cure-all" for depression.

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·December 28, 2020·6 min read

One Psychedelic Experience May Lessen Trauma of Racial Injustice

A single dose of psychedelic treatments can help alleviate symptoms of depression, stress, and trauma in those who have experienced racial injustice.

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·December 22, 2020·5 min read

Cannabis Use Blunts Stress Reactivity

Female rats exposed to vaporized cannabis for 30 days developed a blunted response to stress. The effect was not seen in male rats. Findings shed light on how chronic cannabis use affects males and females differently.

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·December 16, 2020·4 min read

How Does Ketamine Combat Depression?

4E-BPs proteins are key to unlocking ketamine's antidepressant effects. When 4E-BPs are absent in neurons, ketamine can not produce its antidepressant effect.