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peripheral nervous system

This shows an older person walking in a stoop.

·April 17, 2026·8 min read

Could Alzheimer’s Begin in the Nerves, Not the Brain?

Researchers using "human-on-a-chip" technology have found that Alzheimer's-related movement issues may start in the peripheral nerves, rather than the brain, offering a new path for early diagnosis.

Neuroscience

·April 14, 2026·9 min read

Discovery Overturns Longstanding Biology of Human Development

A new study reveals that human peripheral nerve cells commit to their roles much earlier than previously thought, overturning decades of biological assumptions about embryonic development.

Featured Neurology Neuroscience

·January 5, 2020·3 min read

Early prevention of neuropathic pain

Intercepting CCL2 with specific antibodies may provide an early intervention for chronic neuropathic pain.

This shows the outline of two bodies. One has the head highlighted red, the other has the gut highlighted red

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·November 7, 2019·4 min read

Where does Parkinson’s disease start? In the brain or gut? Or both?

Lewy body disorders, including Parkinson's disease and Lewy body dementia, comprise of two distinct subtypes. One subtype originates in the peripheral nervous system (PNS) of the gut and spreads to the brain. The other originates in the brain, or enters the brain via the olfactory system, before spreading to the brainstem and PNS.

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·July 5, 2019·4 min read

Discovery reveals prolific ability of Schwann cells to generate myelin

Schwann cells are much more prolific in generating myelin than previously believed. Knocking out the fbxw7 gene in mouse models, researchers discovered individual Schwann cells began to spread myelin across many axons.

This image shows microglia passing from the CNS to PNS

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·April 7, 2019·4 min read

Microglia, cells thought restricted to central nervous system, are redefined in new study

In response to injury, microglia cross the spinal boundary from the central nervous system to the peripheral nervous system. While in the PNS, microglia provide the function of clearing cellular debris at the point of injury, then return to the CNS in an altered state. Researchers propose this could account for some damage associated with neurodegenerative diseases.

Featured Neurology Open Neuroscience Articles

·October 7, 2017·3 min read

Nerve Study Shows How Cells Adapt to Help Repair Damage

A Cell Reports study identifies molecules that allow Schwann cells to help regenerate nerves.

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·April 9, 2017·6 min read

Discovery of ‘Mini-Brains’ Could Change Understanding of Pain Medication

Findings could help with the development of new painkillers to target back pain, arthritis and other pain disorders.

Featured Neurology

·January 4, 2017·2 min read

Understanding the Causes of Neurological Abnormalities That Result From Premature Birth

Researchers report motor problems associated with preterm birth could be due to defects in peripheral nerves.

Featured Neurology

·August 26, 2016·3 min read

Researchers Report New Zika Complication

Researchers have identified a new neurological complication associated with Zika infection.

Featured Genetics

·August 3, 2016·5 min read

Novel Genetic Mutation May Lead to the Progressive Loss of Motor Function

Researchers have identified a mechanism that appears to be responsible for a rare form of pediatric neuropathy.

Autism Featured Neuroscience Open Neuroscience Articles

·June 9, 2016·5 min read

Autism is Not Just a Disease of the Brain: Mouse Study

A new study reports some aspects of autism spectrum disorders are linked to defects in how peripheral nerves communicate sensory information to the brain.

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