A new study reports some aspects of autism spectrum disorders are linked to defects in how peripheral nerves communicate sensory information to the brain.
Findings could help with the development of new painkillers to target back pain, arthritis and other pain disorders.
Schwann cells are much more prolific in generating myelin than previously believed. Knocking out the fbxw7 gene in mouse models, researchers discovered individual Schwann cells began to spread myelin across many axons.
Intercepting CCL2 with specific antibodies may provide an early intervention for chronic neuropathic pain.
In response to injury, microglia cross the spinal boundary from the central nervous system to the peripheral nervous system. While in the PNS, microglia provide the function of clearing cellular debris at the point of injury, then return to the CNS in an altered state. Researchers propose this could account for some damage associated with neurodegenerative diseases.
The researchers knocked out the Erk gene during peripheral nervous system development in mice. The researchers noticed the neurons of these knock-out mice were largely unaffected, but Schwann cells were "just devastated at every stage of development."
A Cell Reports study identifies molecules that allow Schwann cells to help regenerate nerves.
Researchers have identified a mechanism that appears to be responsible for a rare form of pediatric neuropathy.
Researchers have identified a new neurological complication associated with Zika infection.
Researchers uncover a key to the development of the peripheral nervous system, providing new hope to patients suffering from hereditary neuropathy.
Advances in robotics have made it possible to create artificial legs that can duplicate the natural movement of human legs. The research could help improve the mobility of lower-limb amputees.
A new study reveals how Schwann cells in the PNS degrade myelin following nerve injury.
