peripheral nervous system

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peripheral nervous system

Electrophysiology Featured Genetics Neuroscience

·January 27, 2011·3 min read

Myelination, Schwann Cells Devastated in Erk Knock-out Mice

The researchers knocked out the Erk gene during peripheral nervous system development in mice. The researchers noticed the neurons of these knock-out mice were largely unaffected, but Schwann cells were "just devastated at every stage of development."

The image is a diagram of the nervous system. The Peripheral nervous system is outlined in blue.

Featured Neurology Open Neuroscience Articles

·May 28, 2013·2 min read

Researchers Uncover Key to Development of Peripheral Nervous System

Researchers uncover a key to the development of the peripheral nervous system, providing new hope to patients suffering from hereditary neuropathy.

This is the robotic leg, shown from a frontal view.

Featured Robotics

·November 8, 2013·4 min read

Robotic Advances Promise Artificial Legs That Emulate Healthy Limbs

Advances in robotics have made it possible to create artificial legs that can duplicate the natural movement of human legs. The research could help improve the mobility of lower-limb amputees.

This image shows the proposed role of myelinophagy in a Schwann cell after nerve injury and axon degeneration.

Featured Neuroscience

·July 6, 2015·4 min read

Schwann Cells Clear Damaged Myelin and Guide Regeneration Following Nerve Damage

A new study reveals how Schwann cells in the PNS degrade myelin following nerve injury.

Autism Featured Neuroscience Open Neuroscience Articles

·June 9, 2016·5 min read

Autism is Not Just a Disease of the Brain: Mouse Study

A new study reports some aspects of autism spectrum disorders are linked to defects in how peripheral nerves communicate sensory information to the brain.

Featured Genetics

·August 3, 2016·5 min read

Novel Genetic Mutation May Lead to the Progressive Loss of Motor Function

Researchers have identified a mechanism that appears to be responsible for a rare form of pediatric neuropathy.

Featured Neurology

·August 26, 2016·3 min read

Researchers Report New Zika Complication

Researchers have identified a new neurological complication associated with Zika infection.

Featured Neurology

·January 4, 2017·2 min read

Understanding the Causes of Neurological Abnormalities That Result From Premature Birth

Researchers report motor problems associated with preterm birth could be due to defects in peripheral nerves.

Featured Neurology Neuroscience Neuroscience Videos Open Neuroscience Articles Pain

·April 9, 2017·6 min read

Discovery of ‘Mini-Brains’ Could Change Understanding of Pain Medication

Findings could help with the development of new painkillers to target back pain, arthritis and other pain disorders.

Featured Neurology Open Neuroscience Articles

·October 7, 2017·3 min read

Nerve Study Shows How Cells Adapt to Help Repair Damage

A Cell Reports study identifies molecules that allow Schwann cells to help regenerate nerves.

This image shows microglia passing from the CNS to PNS

Featured Neuroscience Open Neuroscience Articles

·April 7, 2019·4 min read

Microglia, cells thought restricted to central nervous system, are redefined in new study

In response to injury, microglia cross the spinal boundary from the central nervous system to the peripheral nervous system. While in the PNS, microglia provide the function of clearing cellular debris at the point of injury, then return to the CNS in an altered state. Researchers propose this could account for some damage associated with neurodegenerative diseases.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·July 5, 2019·4 min read

Discovery reveals prolific ability of Schwann cells to generate myelin

Schwann cells are much more prolific in generating myelin than previously believed. Knocking out the fbxw7 gene in mouse models, researchers discovered individual Schwann cells began to spread myelin across many axons.

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