The epigenetic histone mutation H3.1K27M works in combination with ACVR1 mutations to cause diffuse intrinsic pontine glioma tumors to form and grow quickly. Read More
Dysregulation of Zfp36l1 causes neural lineage progenitor cells to grow rapidly, taking on the properties of fast growing stem cells as they become cancerous. Read More
DIPG cancer cells exposed to MI-2 fail to maintain healthy levels of cholesterol and die quickly, by inhibiting lanosterol synthase. Additionally, while MI-2 destroys glioma cancer cells, the drug does not damage healthy brain cells. Read More
Researchers use PET neuroimaging technology to help determine which children with DIPG brain cancer will benefit best from Avastin. Read More
A new study reports on the benefits of precision medicine for treating pediatric brain cancer. Read More
