Brain CancerFeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles·May 16, 2019·4 min readMutations Synergize in Pediatric Brain CancerThe epigenetic histone mutation H3.1K27M works in combination with ACVR1 mutations to cause diffuse intrinsic pontine glioma tumors to form and grow quickly.Read More
Brain CancerFeaturedGeneticsNeurologyNeuroscience·April 11, 2019·4 min readShutting down deadly pediatric brain cancer at its earliest momentsDysregulation of Zfp36l1 causes neural lineage progenitor cells to grow rapidly, taking on the properties of fast growing stem cells as they become cancerous.Read More
Brain CancerFeaturedNeurologyNeuroscience·April 6, 2019·4 min readNew hope for treating childhood brain cancerDIPG cancer cells exposed to MI-2 fail to maintain healthy levels of cholesterol and die quickly, by inhibiting lanosterol synthase. Additionally, while MI-2 destroys glioma cancer cells, the drug does not damage healthy brain cells.Read More
Brain CancerFeaturedNeurology·May 2, 2017·4 min readPET/CT Helps Predict Therapy Effectiveness in Pediatric Brain TumorsResearchers use PET neuroimaging technology to help determine which children with DIPG brain cancer will benefit best from Avastin.Read More
Brain CancerFeaturedGeneticsNeurology·January 21, 2017·6 min readNew Hope For Children With Brain TumorsA new study reports on the benefits of precision medicine for treating pediatric brain cancer.Read More