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Parkinson’s disease

·August 12, 2019·3 min read

Estrogen improves Parkinson’s disease symptoms

Selective estrogen treatments appear to reduce symptoms of Parkinson's disease in male mice. The study sheds light on sex-based differences associated with the disease and may provide new therapeutic avenues for treatment.

This shows how ultrasound frequency affects different mammals

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·August 11, 2019·6 min read

The new field of sonogenetics uses sound waves to control the behavior of brain cells

A new technology known as sonogenetics can control neural activity by using sound frequencies. The technology could be used to non-invasively treat a range of neurological conditions, including Parkinson's disease and epilepsy.

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·August 7, 2019·2 min read

Low vitamin D levels linked to non-motor symptoms in patients with Parkinson’s disease

Vitamin D supplementation may help reduce some of the non-motor symptoms associated with Parkinson's disease.

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·July 29, 2019·4 min read

Discovery could lead to new treatments for Parkinson’s, other brain diseases

New model could inform the development of new treatments for Lewy body diseases by targeting alpha-synuclein DNA repair mechanisms.

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·July 24, 2019·3 min read

Stimulation of the ear can help manage Parkinson’s symptoms

A headset that stimulates the ear canal improves both motor and non-motor symptoms of Parkinson's disease. The effects of the stimulation appear to have a lasting effect following treatment.

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·July 19, 2019·3 min read

Taking out the Protein Garbage Becomes More Difficult as Neurons Age

In aging mice, the number of autophagosomes is significantly decreased, and pronounced defects in the structure of autophagosomes increased. Turning on the WIPI2B protein restores autophagosome formation in aged neurons.

The gut and brain are highlighted in this drawing of a man

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·July 17, 2019·5 min read

Bacterial intestinal infections may trigger Parkinson’s disease

Mice infected with bacteria that cause mild intestinal infections exhibited Parkinson's like symptoms later in life. The findings provide a pathophysiological model in which intestinal infections may act as a trigger for Parkinson's disease.

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·July 16, 2019·3 min read

Antioxidant precursor molecule could improve Parkinson’s

N-acetylcysteine (NAC) appears to positively affect the dopaminergic system, helping to improve symptoms in those with Parkinson's disease.

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·July 9, 2019·4 min read

Sorting protein in neurons defends against neurodegenerative disease

VPS35 is a novel critical component of tau metabolism and the pathology of neurodegenerative diseases.

This shows two head outlines with drawings of brains in them

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·July 6, 2019·4 min read

To cure brain diseases, neuroscientists must collaborate: That’s why I’m giving my data away

Open sharing of scientific data and standard methods will allow researchers to collaborate on projects and accelerate understanding of neurodegenerative diseases.

This is a schematic of the mouse olfactory system

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·July 1, 2019·4 min read

Sense of smell, pollution and neurological disease connection explored

Damaged olfactory neurons as a result of air pollution may contribute to altered cerebrospinal fluid flow and turnover, acting as a potential mechanism for the development of neurodegenerative diseases.

This diagram shows how a-synuclein travels from the gut to the brain via the vagus nerve

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·June 26, 2019·6 min read

New research shows Parkinson’s disease origins in the gut

A new study adds to the growing body of evidence that Parkinson's disease may start in the gut. Researchers found gut-to-brain propagation of alpha-synuclein spread via the vagus nerve. The study provides a more accurate model of Parkinson's progression and could lead to new treatments to halt or prevent this neurodegenerative disease.