Researchers discover a link between brain development and the BRAC1, a gene associated with breast cancer.
Researchers report that, at the molecular levels, aging may have originated at the beginning of the evolution of life. They suggest when it comes to genes, aging may not always be a negative trait, and may help an organism to survive.
Scientists have long believed that glioblastoma multiforme, the most aggressive type of primary brain tumor, begins in glial cells that make up supportive tissue in the brain or in neural stem cells. Researchers found that the tumors can originate from other types of differentiated cells in the nervous system, including cortical neurons.
Researchers are turning to supercomputers in the quest to discover new treatments and targets for cancers.
Researchers use gene editing to generate aggressive glioblastoma multiforme brain tumors in the lab. The model, researchers say, could be used to track the progression of tumors and develop personalized therapies for patients.
PPCA treatment shown to provide therapeutic benefit in mouse models of hemophagocytic lymphohistiocytosis and multiple sclerosis.
A new drug could help increase the effectiveness of radiation therapy for patients with glioblastoma multiforme, the most deadly form of brain cancer. The ATM kinase inhibitor, in combination with radiation therapy, helped significantly extend survival rates in mouse models of GBM.
In males, sun exposure activates the p53 protein which signals to the body to produce the appetite-associated ghrelin hormone. In women, estrogen blocks the interaction between p53 and ghrelin, reducing the urge to eat following sun exposure.