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mitochondria

Featured Genetics Neurology Neuroscience

·July 15, 2019·5 min read

Differences in MS patients’ cerebrospinal fluid may be key to drugs that halt progression

Ceramide exposure impairs the ability for neurons to make energy by directly damaging mitochondria. Additionally, ceramides force neurons to rapidly uptake glucose in order to provide cellular energy.

Featured Genetics Neurology Neuroscience

·June 21, 2019·4 min read

A new drug target for chemically induced Parkinson’s disease

Mitochondrial CYP2D6 may be a powerful target for the treatment of Parkinson's disease induced by MPTP.

Featured Genetics Neurology

·May 20, 2019·3 min read

Researchers link new protein to Parkinson’s

The MITOL protein has been implicated in Parkinson's disease.

This shows a cell with mitochondrial damage

Featured Genetics Neurology Neuroscience

·May 16, 2019·3 min read

Miro2 is a Parkin receptor for selective removal of damaged mitochondria

Findings from a mouse model study reveal Miro2 functions as a platform for Parkin translocation and damaged mitochondrial clearance.

Featured Genetics Neuroscience

·May 9, 2019·4 min read

Neurodevelopmental disorders may be rooted in genetics and mitochondrial deficits: Mouse study

Mouse models of DiGeorge/22q1 Deletion Syndrome reveal a connection between mitochondrial dysfunction, deficits in cortical connectivity and cognitive impairments. Function was restored through antioxidant therapy.

This flow diagram shows the link between mitochondria, health and aging

Featured Neuroscience

·May 8, 2019·2 min read

Mitochondrial function may explain link between intelligence, health and aging

Mitochondrial function may help explain the link between intelligence, general health and aging.

This flow chart shows how BH3-only binds with BAX in apoptosis

Featured Genetics Neuroscience Open Neuroscience Articles

·April 9, 2019·4 min read

Cell death may be triggered by ‘hit-and-run’ interaction

Two different parts to the BAX protein can bind to BH3-only, and these sites function at different stages of BAX activation. When BH3-only binds to one of the regions, BAX becomes able to damage mitochondria.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·April 7, 2019·4 min read

New insights into proteins key to Charcot-Marie-Tooth and other nerve diseases

Increasing levels of the MFN1 protein counterbalances mutated MFN2, reducing symptoms associated with Charcot-Marie-Tooth disease and neurodegeneration in mouse models.

Featured Genetics Neurology Open Neuroscience Articles

·February 15, 2019·4 min read

Researchers Describe First Model of Mitochondrial Epilepsy

Researchers have developed a new model of mitochondrial epilepsy which captures specific features observed in patients. The new model may help provide better therapies and treatments for the condition.

Featured Genetics Neurology

·February 15, 2019·3 min read

‘Lack of Cleaning’ in Brain Cells is Central to Alzheimer’s

Researchers report dysfunctional mitophagy may contribute to the development of Alzheimer's disease. When mitophagy is improved, symptoms of Alzheimer's almost disappeared in animal models of the disease.

Featured Genetics Neuroscience Open Neuroscience Articles Psychology

·January 7, 2019·3 min read

Anxiety and Depressive Disorders Alter Brain Gene Activity

Researchers depression and anxiety alters energy metabolism in the brain.

Featured Genetics Neurology Neuroscience Psychology

·January 4, 2019·13 min read

The Mysteries of the Super-Ager Revealed

Scientific research is helping to unlock the secrets behind why some people live to become super-agers. Researchers propose ways in which we can slow the aging process and extend our life spans.