FeaturedGeneticsNeurologyNeuroscience·July 17, 2019·5 min readBacterial intestinal infections may trigger Parkinson’s diseaseMice infected with bacteria that cause mild intestinal infections exhibited Parkinson's like symptoms later in life. The findings provide a pathophysiological model in which intestinal infections may act as a trigger for Parkinson's disease.Read More
FeaturedNeurologyNeurosciencePsychology·July 15, 2019·4 min readThe human microbiome is a treasure trove waiting to be unlockedUnderstanding the complexity of the human microbiome may help unlock mysteries behind health and psychological illnesses.Read More
FeaturedGeneticsNeurologyNeuroscience·July 15, 2019·5 min readDifferences in MS patients’ cerebrospinal fluid may be key to drugs that halt progressionCeramide exposure impairs the ability for neurons to make energy by directly damaging mitochondria. Additionally, ceramides force neurons to rapidly uptake glucose in order to provide cellular energy.Read More
FeaturedGeneticsNeurologyNeuroscience·June 21, 2019·4 min readA new drug target for chemically induced Parkinson’s diseaseMitochondrial CYP2D6 may be a powerful target for the treatment of Parkinson's disease induced by MPTP.Read More
FeaturedGeneticsNeurology·May 20, 2019·3 min readResearchers link new protein to Parkinson’sThe MITOL protein has been implicated in Parkinson's disease.Read More
FeaturedGeneticsNeurologyNeuroscience·May 16, 2019·3 min readMiro2 is a Parkin receptor for selective removal of damaged mitochondriaFindings from a mouse model study reveal Miro2 functions as a platform for Parkin translocation and damaged mitochondrial clearance.Read More
FeaturedGeneticsNeuroscience·May 9, 2019·4 min readNeurodevelopmental disorders may be rooted in genetics and mitochondrial deficits: Mouse studyMouse models of DiGeorge/22q1 Deletion Syndrome reveal a connection between mitochondrial dysfunction, deficits in cortical connectivity and cognitive impairments. Function was restored through antioxidant therapy.Read More
FeaturedNeuroscience·May 8, 2019·2 min readMitochondrial function may explain link between intelligence, health and agingMitochondrial function may help explain the link between intelligence, general health and aging.Read More
FeaturedGeneticsNeuroscienceOpen Neuroscience Articles·April 9, 2019·4 min readCell death may be triggered by ‘hit-and-run’ interactionTwo different parts to the BAX protein can bind to BH3-only, and these sites function at different stages of BAX activation. When BH3-only binds to one of the regions, BAX becomes able to damage mitochondria.Read More
FeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles·April 7, 2019·4 min readNew insights into proteins key to Charcot-Marie-Tooth and other nerve diseasesIncreasing levels of the MFN1 protein counterbalances mutated MFN2, reducing symptoms associated with Charcot-Marie-Tooth disease and neurodegeneration in mouse models.Read More
FeaturedGeneticsNeurologyOpen Neuroscience Articles·February 15, 2019·4 min readResearchers Describe First Model of Mitochondrial EpilepsyResearchers have developed a new model of mitochondrial epilepsy which captures specific features observed in patients. The new model may help provide better therapies and treatments for the condition.Read More
FeaturedGeneticsNeurology·February 15, 2019·3 min read‘Lack of Cleaning’ in Brain Cells is Central to Alzheimer’sResearchers report dysfunctional mitophagy may contribute to the development of Alzheimer's disease. When mitophagy is improved, symptoms of Alzheimer's almost disappeared in animal models of the disease.Read More
