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mitochondria

This flow chart shows how BH3-only binds with BAX in apoptosis

Featured Genetics Neuroscience Open Neuroscience Articles

·April 9, 2019·4 min read

Cell death may be triggered by ‘hit-and-run’ interaction

Two different parts to the BAX protein can bind to BH3-only, and these sites function at different stages of BAX activation. When BH3-only binds to one of the regions, BAX becomes able to damage mitochondria.

Electrophysiology Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·January 12, 2020·4 min read

Neurons’ energy organelle protected from damage linked to ALS & Alzheimer’s

Researchers have identified a set of drug-like compounds, including a common ingredient in throat lozenges, that can help protect mitochondria from the stresses associated with neurodegenerative diseases.

Featured Genetics Neurology

·May 20, 2019·3 min read

Researchers link new protein to Parkinson’s

The MITOL protein has been implicated in Parkinson's disease.

Featured Genetics Neuroscience Psychology

·August 21, 2023·5 min read

Unlocking Schizophrenia: Mitochondria Dysfunction at the Forefront

Researchers have identified a pivotal role of impaired mitochondrial function in the development of schizophrenia by examining the genetic risk factor 3q29 deletion syndrome. The genetic condition, known to amplify schizophrenia risk by 40 times, displayed alterations in mitochondrial activity in both mice models and human brain organoids.

This image shows a graphic representation of mitochondria.

Featured Genetics Open Neuroscience Articles

·October 13, 2014·4 min read

Greater Rates of Mitochondrial Mutations Discovered in Children Born to Older Mothers

Researchers report finding greater rates of mitochondrial mutations in the offspring of older mothers, as well as the mothers themselves.

Featured Genetics

·October 10, 2016·3 min read

Cell Protein Offers New Hope in Fighting the Effects of Aging

A new study could be the first step to developing drugs that targets carbonic anhydrase in mitochondria to help protect against aging and neurodegeneration.

Featured Neuroscience Open Neuroscience Articles Psychology

·November 27, 2021·5 min read

Looking to Mitochondria for Clues About Depression

People with untreated depression have lower levels of mitochondrial proteins. For those who responded to the SSRI antidepressants, the proteins returned to a normal level, but showed no increase in those who did not respond to medication.

Featured Genetics Neuroscience

·August 13, 2020·4 min read

Becoming a Nerve Cell: Timing Is of the Essence

Mitochondria regulate how neural stem cells become neurons during brain development. The findings may help explain how humans developed larger brains during evolution and how mitochondrial defects lead to some neurodevelopmental disorders.

Featured Neurology

·February 26, 2016·4 min read

Researchers Suppress Alzheimer’s Associated Neuronal Death and Oxidative Stress

Researchers have successfully designed mitochondria-specific ceria nanoparticles which appear to be capable of suppressing neuronal death associated with Alzheimer's disease.

a cup of coffee with a heart in the foam

Featured Genetics Neurology Open Neuroscience Articles

·June 22, 2018·3 min read

Caffeine From Four Cups of Coffee Protects the Heart With the Help of Mitochondria

A new study reports caffeine concentration, the equivalent of four cups of coffee, can promote the movement of a regulatory protein into mitochondria. This can enhance mitochondrial function and protect heart cells from damage.

Featured Genetics Neurology Neuroscience Psychology

·January 4, 2019·13 min read

The Mysteries of the Super-Ager Revealed

Scientific research is helping to unlock the secrets behind why some people live to become super-agers. Researchers propose ways in which we can slow the aging process and extend our life spans.