A new study appears to build on the previous research that suggests genetic mutations which affect mitochondria function could be critical to the development and progression of Alzheimer's disease.
Inhibition of the Drp1 mitochondrial fission protein shows potential as a treatment for Parkinson's disease.
Researchers have identified genetics mutations involved in a rare and unnamed neurological disorder.
An experimental small molecule helped restore the removal of mitochondria from dopamine-producing neurons in the brain. The findings may help in the development of new therapies for Parkinson's disease.
Increasing levels of the MFN1 protein counterbalances mutated MFN2, reducing symptoms associated with Charcot-Marie-Tooth disease and neurodegeneration in mouse models.
A new Nature Neuroscience study provides evidence that necroptosis is linked to cognitive decline and severity of Alzheimer's disease. The finding that necroptosis is activated in Alzheimer's provides a plausible mechanism that underlies the neuron loss associated with the disease.
Researchers have captured the structural dynamics of the mitochondrion using fluorescent probes. This mapping could provide insights into the underlying causes of neurodegeneration associated with mitochondrial malfunction.
Researchers report two genes associated with Parkinson's disease are also key regulators of the immune system.
Researchers believe that, given time, mitochondria can recover their normal form following TBI or stroke.