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microscopy

·August 28, 2021·4 min read

First Atomic-Level Imaging of Lethal Prions Provide Sharpened Focus for Potential Treatments

Cryogenic-electron microscopy allowed researchers to determine the basic building blocks of prion proteins, including the placements of their amino acids.

This shows two different images of a mouse brain. One is colored by the DOLI method

Featured Neuroscience

·May 27, 2021·4 min read

A Deep Dive Into the Brain

Diffuse optical localization imaging (DOLI) is a newly developed fluorescence microscopy technique that allows for high-resolution imaging of microcirculation in a non-invasive manner.

This shows images of the developing brain

Featured Neuroscience

·February 24, 2021·4 min read

Capturing the Choreography of a Developing Brain

Combining microscopy with artificial intelligence, researchers were able to visualize the complex architecture of interconnected neurons in live C. elegans.

This shows neurons from a schizophrenia patient

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·February 23, 2021·5 min read

Seeing Schizophrenia: X-Rays Shed Light on Neural Differences

Neurons from brain tissue samples of people with schizophrenia showed greater deviation, both from neurons from samples of people without the condition and from others with schizophrenia. Researchers say the structure of the neurons is unique to each individual with schizophrenia.

This shows dendritic spines on hippocampal neurons

Featured Neuroscience

·October 13, 2020·4 min read

A New Approach to Analyzing the Morphology of Dendritic Spines

A clusterization approach allows researchers to analyze dendritic spines in new ways.

This shows a drawing of a rat with the flexiscope

Featured Neuroscience

·May 19, 2020·3 min read

Observing the freely behaving brain in action

A newly developed head-mounted miniature microscope can capture images of all cortical layers of a freely moving rat.

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·May 4, 2020·3 min read

Imaging technology allows visualization of nanoscale structures inside whole cells

New microscopy technology images the position of biomolecules with precision down to a few nanometers inside whole cells and tissues.

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·April 16, 2020·2 min read

Insight into the synapses

The direct contact of mGluR4 receptors with other key proteins plays a significant role in the regulation of synaptic activity.

This shows blood vessels under the 2 photo microscope

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·March 21, 2020·7 min read

High-speed microscope captures fleeting brain signals

Combining two-photon fluorescent microscopy and all-optical laser scanning, researchers can image the brain of an alert mouse 1,000 times a second, recording the passage of millisecond electrical pulses through neurons.

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·March 18, 2020·4 min read

Ball-and-chain inactivation of ion channels visualized by cryo-electron microscopy

Ion channels use a "ball-and-chain" mechanism to help regulate ion flow. Findings confirm a long-standing hypothesis about ion channels and provide key advances in understanding the basic biological processes at work.

Featured Neuroscience

·March 12, 2020·4 min read

Using machine learning to analyze whole brain vasculature

Combining advance microscopy techniques and artificial intelligence, researchers reconstruct the entire vascular network of a mouse brain down to its finest details.

$This shows neurons$