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metabolism

·December 2, 2024·6 min read

Personal Gut Environments Shape How We Digest, Absorb Food

Individual differences in gut physiology and environment play a major role in shaping our gut microbiome and how we process food. Using a smart capsule to measure pH, temperature, and pressure, researchers found significant variations in digestion time and gut conditions between people.

This shows an AI representation of mitochondria.

Featured Genetics Neuroscience

·November 22, 2024·4 min read

Mitochondrial Gene Editing Reveals Links to Memory

Researchers used mitochondrial gene editing to model genetic disorders in mice, revealing profound impacts on brain function, metabolism, and thermoregulation. They employed a specialized DNA editing tool to induce mutations in the ND5 mitochondrial gene, disrupting energy production and causing learning deficits, hippocampal atrophy, and obesity.

Featured Neuroscience

·November 12, 2024·4 min read

Natural Compound BHB-Phe Regulates Appetite

Scientists have identified BHB-Phe, a natural compound produced by the body, that regulates appetite and body weight. By activating specific brain neurons, BHB-Phe suppresses feeding behavior in mice, suggesting potential therapeutic applications for obesity.

Featured Neuroscience

·October 8, 2024·3 min read

Sex-Based Breakfast Choices May Boost Metabolism

A recent study using mathematical models suggests that breakfast choices may affect men’s and women’s metabolisms differently. Results indicate that men’s metabolisms respond better to carb-heavy breakfasts, while women’s bodies benefit more from higher-fat options like eggs or avocados, especially after fasting.

Featured Neurology Neuroscience

·September 27, 2024·5 min read

Metabolic Disruptions in Parkinson’s Uncover New Treatment Potential

A new study has revealed critical metabolic impairments in Parkinson’s disease (PD), focusing on purine metabolism and ATP recycling. Researchers found that patients with PD have significantly lower levels of uric acid and other purine metabolites in their blood and cerebrospinal fluid, affecting energy production in the brain.

Featured Neuroscience

·May 19, 2024·6 min read

Sweet Taste Receptors Play Role in Glucose Metabolism

The sweet taste receptor, TAS1R2-TAS1R3, plays a dual role in regulating glucose metabolism. Stimulating this receptor with sucralose accelerates insulin release, while inhibiting it with lactisole slows insulin release. This finding suggests that targeting TAS1R2-TAS1R3 could offer new therapeutic avenues for managing metabolic disorders like diabetes.

Autism Featured Neuroscience

·May 10, 2024·5 min read

Early Metabolic Changes Linked to Autism

Researchers discovered significant metabolic changes that occur between birth and the onset of autism spectrum disorder (ASD) symptoms. This study reveals that a few biochemical pathways, related largely to the body's cell danger response, are responsible for the majority of these changes.

Featured Neuroscience

·April 29, 2024·5 min read

Brown Fat’s “Off Switch” Discovery Combats Obesity

Researchers have made significant discoveries about brown adipose tissue (BAT), which is known for its calorie-burning capabilities. Their study identifies a protein, AC3-AT, that acts as an "off switch" for BAT activation, limiting its effectiveness in combating obesity. By potentially blocking this switch, the researchers believe they can enhance brown fat's activity, offering a new avenue for treating obesity and related metabolic disorders.

Featured Neuroscience

·April 25, 2024·4 min read

Sight and Smell of Food Kickstarts Liver Activity

Merely seeing and smelling food can activate adaptations in liver mitochondria in mice within minutes. This response is driven by the activation of POMC neurons in the brain, signaling the liver to prepare for nutrient processing by modifying mitochondrial protein through phosphorylation.

Featured Neurology Neuroscience

·April 24, 2024·7 min read

Spinal Injuries Trigger Metabolic Disorders

A new study demonstrates how spinal cord injuries can lead to significant metabolic disruptions, including the onset of conditions such as diabetes and heart disease. The study found that abnormal neuronal activities post-injury lead to excessive breakdown of triglycerides in fat tissue, releasing harmful compounds into organs like the liver.

This shows a hand covered in plastic beads.

Featured Neuroscience

·April 15, 2024·7 min read

Microplastics Journey from Gut to Vital Organs

A new study highlights the alarming infiltration of microplastics into human tissues, including the kidney, liver, and brain. The study investigates how these tiny particles, commonly ingested through water, food, and air, breach the gastrointestinal tract to affect major organs and metabolic pathways.

This shows a man eating a plate of food.

Featured Neuroscience Psychology

·April 1, 2024·7 min read

Keto Diet May Improve Mental Health Symptoms

A new pilot study presents a compelling case for the ketogenic diet as a dual-action treatment for individuals with serious mental illnesses like schizophrenia and bipolar disorder, who often suffer metabolic side effects from their medication. The research shows how adopting a ketogenic diet not only mitigates these metabolic issues but also significantly improves psychiatric conditions.

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metabolism

Personal Gut Environments Shape How We Digest, Absorb Food

Mitochondrial Gene Editing Reveals Links to Memory

Natural Compound BHB-Phe Regulates Appetite

Sex-Based Breakfast Choices May Boost Metabolism

Metabolic Disruptions in Parkinson’s Uncover New Treatment Potential

Sweet Taste Receptors Play Role in Glucose Metabolism

Early Metabolic Changes Linked to Autism

Brown Fat’s “Off Switch” Discovery Combats Obesity

Sight and Smell of Food Kickstarts Liver Activity

Spinal Injuries Trigger Metabolic Disorders

Microplastics Journey from Gut to Vital Organs

Keto Diet May Improve Mental Health Symptoms

Healthy Plant-Based Eating Lowers Dementia Risk

Estrogen Levels at the Moment of Trauma Predict PTSD

Toddler Habits Predict Teenage Fitness

Brain’s Endurance Program: Hypothalamus Remembers Exercise

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