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metabolism

·May 19, 2024·6 min read

Sweet Taste Receptors Play Role in Glucose Metabolism

The sweet taste receptor, TAS1R2-TAS1R3, plays a dual role in regulating glucose metabolism. Stimulating this receptor with sucralose accelerates insulin release, while inhibiting it with lactisole slows insulin release. This finding suggests that targeting TAS1R2-TAS1R3 could offer new therapeutic avenues for managing metabolic disorders like diabetes.

Autism Featured Neuroscience

·May 10, 2024·5 min read

Early Metabolic Changes Linked to Autism

Researchers discovered significant metabolic changes that occur between birth and the onset of autism spectrum disorder (ASD) symptoms. This study reveals that a few biochemical pathways, related largely to the body's cell danger response, are responsible for the majority of these changes.

Featured Neuroscience

·April 29, 2024·5 min read

Brown Fat’s “Off Switch” Discovery Combats Obesity

Researchers have made significant discoveries about brown adipose tissue (BAT), which is known for its calorie-burning capabilities. Their study identifies a protein, AC3-AT, that acts as an "off switch" for BAT activation, limiting its effectiveness in combating obesity. By potentially blocking this switch, the researchers believe they can enhance brown fat's activity, offering a new avenue for treating obesity and related metabolic disorders.

Featured Neuroscience

·April 25, 2024·4 min read

Sight and Smell of Food Kickstarts Liver Activity

Merely seeing and smelling food can activate adaptations in liver mitochondria in mice within minutes. This response is driven by the activation of POMC neurons in the brain, signaling the liver to prepare for nutrient processing by modifying mitochondrial protein through phosphorylation.

Featured Neurology Neuroscience

·April 24, 2024·7 min read

Spinal Injuries Trigger Metabolic Disorders

A new study demonstrates how spinal cord injuries can lead to significant metabolic disruptions, including the onset of conditions such as diabetes and heart disease. The study found that abnormal neuronal activities post-injury lead to excessive breakdown of triglycerides in fat tissue, releasing harmful compounds into organs like the liver.

This shows a hand covered in plastic beads.

Featured Neuroscience

·April 15, 2024·7 min read

Microplastics Journey from Gut to Vital Organs

A new study highlights the alarming infiltration of microplastics into human tissues, including the kidney, liver, and brain. The study investigates how these tiny particles, commonly ingested through water, food, and air, breach the gastrointestinal tract to affect major organs and metabolic pathways.

This shows a man eating a plate of food.

Featured Neuroscience Psychology

·April 1, 2024·7 min read

Keto Diet May Improve Mental Health Symptoms

A new pilot study presents a compelling case for the ketogenic diet as a dual-action treatment for individuals with serious mental illnesses like schizophrenia and bipolar disorder, who often suffer metabolic side effects from their medication. The research shows how adopting a ketogenic diet not only mitigates these metabolic issues but also significantly improves psychiatric conditions.

Featured Genetics Neuroscience Psychology

·March 27, 2024·7 min read

THC Metabolism Could Influence Cannabis Use Disorder Risk

Researchers linked differences in THC metabolism to varying effects of cannabis use and the risk of developing Cannabis Use Disorder (CUD). The study, which included young adults with and without CUD, found that genetic differences in THC-metabolizing enzymes can lead to stronger and longer-lasting effects of cannabis, especially among females who metabolize THC more slowly.

Featured Neuroscience

·March 1, 2024·4 min read

What Happens to the Body During Prolonged Fasting?

A new study illuminated the extensive molecular changes that occur in the body during prolonged fasting. Monitoring 12 healthy volunteers on a seven-day water-only fast, the study identified significant shifts in around 3,000 proteins across all major organs, with notable changes only becoming apparent after three days of fasting.

Featured Neuroscience Psychology

·December 15, 2023·7 min read

Metabolic Markers of Depression Identified

Researchers revealed a crucial link between cellular metabolism and major depressive disorder, particularly in treatment-refractory cases and suicidal ideation. This research found specific blood metabolites that differ in people with depression, providing new biomarkers for risk assessment.

Featured Neurology Neuroscience

·November 1, 2023·5 min read

Metabolic Rise in Hippocampus Unveils Alzheimer’s Early Footprint

Researchers reveal a surprising early phase in Alzheimer’s disease development: a metabolic boost in the hippocampus. Studying mice resembling human Alzheimer's pathology, they observed increased mitochondrial metabolism followed by synaptic disruptions due to hindered cellular recycling.

Featured Neuroscience

·July 6, 2023·3 min read

The Human Heat Limit: Metabolic Rates Spike at 104-122°F

Researchers have discovered an upper critical temperature (UCT) for humans, likely between 104-122°F (40°C-50°C). Their research indicates that the human body's resting metabolic rate, an indicator of energy consumption, rises in hot and humid conditions.

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metabolism

Sweet Taste Receptors Play Role in Glucose Metabolism

Early Metabolic Changes Linked to Autism

Brown Fat’s “Off Switch” Discovery Combats Obesity

Sight and Smell of Food Kickstarts Liver Activity

Spinal Injuries Trigger Metabolic Disorders

Microplastics Journey from Gut to Vital Organs

Keto Diet May Improve Mental Health Symptoms

THC Metabolism Could Influence Cannabis Use Disorder Risk

What Happens to the Body During Prolonged Fasting?

Metabolic Markers of Depression Identified

Metabolic Rise in Hippocampus Unveils Alzheimer’s Early Footprint

The Human Heat Limit: Metabolic Rates Spike at 104-122°F

How Severe Illness During Pregnancy Alters Fetal Brain Development

Aging Brains Maintain Robust Language Networks Despite Cognitive Decline

Youth Protein TIMP2 Restores Immune Function in the Aging Brain

Shame, Stigma, and Culture Prevent Male Domestic Violence Survivors From Seeking Help

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