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ketamine

This shows how NV-5138 affects dendrites

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·April 17, 2019·3 min read

New drug mimics benefits of ketamine for depression

NV-5138, a small molecule drug that mimics the action of ketamine, provides fast-acting antidepressant responses in rodent models of depression. The drug is currently undergoing Phase 1 testing in humans.

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·April 11, 2019·3 min read

Ketamine reverses neural changes underlying depression-related behaviors: Mouse study

The formation of prefrontal cortex dendritic spine formation sustains the remission of depressive related symptoms and behaviors following ketamine treatment by restoring lost spines.

This is the chemical structure of ketamine

Featured Neuroscience Psychology

·March 30, 2019·4 min read

Researchers Discover How a Critical Receptor is Involved in the Response to Fast-Acting Antidepressants Like Ketamine

The mGlu2 receptor plays a critical role in the effectiveness of ketamine for treating depression.

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·January 10, 2019·2 min read

Ketamine and Naltrexone Combo Shows Promise for Depression and Addiction Treatments

A new study reveals the combination of ketamine with naltrexone can help treat symptoms of both depression and addiction.

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·December 18, 2018·4 min read

Are Near Death Experiences Hallucinations?

Researchers consider the neurobiology of near death experiences.

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·December 4, 2018·6 min read

New Insights Into Loss of Pleasure in Depression

A new study reveals a brain region that contributes to anhedonia, the loss of pleasure, in those with depression. The study also shows how ketamine acts on this brain region, explaining why the drug appears to be so effective at treating anhedonia.

Featured Neuroscience Psychology

·August 29, 2018·7 min read

Ketamine’s Antidepressant Effects Tied to Opioid System in the Brain

Researchers report ketamine's antidepressive effects require activation of opioid receptors in the brain. The study highlights the interaction between depression, pain and opioid addiction.

Featured Neuroscience Psychology

·June 22, 2018·4 min read

Ketamine Acts Fast to Treat Depression and Its Effects Last, But How?

Researchers explore the mechanisms behind ketamine's effectiveness at treating depression. The study reports the long lasting effects of ketamine may be due to G proteins timing in moving back to lipid rafts.

image shows neurons under psychedelics and ketamine

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·June 12, 2018·4 min read

Ketamine and Psychedelic Drugs Change Structure of Neurons

A new study reveals psychedelics increase dendrites, dendritic spines and synapses, while ketamine may promote neuroplasticity. The findings could help develop new treatments for anxiety, depression and other related disorders.