Random

ketamine

This is the outline of a woman. Inside here head is an illustration of neurons.

·July 31, 2015·4 min read

Over-Active Glutamate Receptor Gene in Females with Depression

According to a new study, postmortem brain tissue from females who suffered from depression had abnormally high expression levels of a number of genes which regulate the glutamate system.

Diagram shows how ketamine affects the brain.

Featured Neurology

·May 11, 2016·3 min read

A ‘Communication Breakdown’ During General Anesthesia

A new study reveals the neurological mechanisms at work during ketamine anesthesia.

Featured Psychology

·August 15, 2017·4 min read

Will Ketamine Treat Your Depression? Check Your Activity Monitor

A new study reports depressed people who responded to ketamine found their activity increased during earlier parts of the day. Researchers suggest clock gene machinery may be linked to the type of depression that responds to ketamine treatment.

Neuroscience

·February 28, 2026·7 min read

Ketamine Revolution: Study Redefines Depression Treatment

Pioneering research into ketamine has moved depression treatment away from slow-acting serotonin drugs toward rapid-acting glutamate therapy.

Featured Psychology

·April 5, 2017·4 min read

Schizophrenia Signs Linked to Uncoordinated Firing of Brain Cells: Mouse Study

Researchers report a group of neurons that fire haphazardly in mouse models of schizophrenia could underlie the psychosis that is symptomatic of the disorder.

Featured Neuroscience Psychology

·December 30, 2022·4 min read

Ketamine Found to Increase Brain Noise

By inhibiting NMDA receptors, ketamine increases noise to gamma frequencies in one layer of the thalamic nucleus and one lay of the somatosensory cortex. Findings suggest psychosis may be triggered by an increase in background noise impairing thalamocortical neurons which may be caused by a malfunction in NMDA receptors affecting the balance of inhibition and excitation in the brain.

Featured Neuroscience Psychology

·September 1, 2019·5 min read

Psychedelic drugs: would you accept a prescription? It depends if you’ve tried them before

Numerous studies have linked controlled psychedelics to improvements in mental health conditions such as depression and PTSD. In March, the FDA approved Esketamine as a treatment for depression. However, with much stigma surrounding psychedelics, researchers question how many patients would take psychedelic medications if prescribed to them. According to a new study, 40% of people with no experience of psychedelics would be unlikely to take the prescription due to fears of 'brain damage' or a 'bad trip'.

Featured Neuroscience Open Neuroscience Articles Psychology

·June 1, 2020·4 min read

How ketamine combats depression

Ketamine increases the number of serotonin 1B receptors. Ketamine binds to serotonin 1B receptors, reducing the release of serotonin and increasing the release of dopamine.

Featured Neuroscience Psychology

·January 10, 2019·2 min read

Ketamine and Naltrexone Combo Shows Promise for Depression and Addiction Treatments

A new study reveals the combination of ketamine with naltrexone can help treat symptoms of both depression and addiction.

Featured Neuroscience Psychology

·May 19, 2026·16 min read

Buprenorphin and Ketamine Combo Provide Anti-Suicidal Effect

A sequential combination of a single ketamine infusion followed by four weeks of low-dose daily buprenorphine successfully extends the antisuicidal window of ketamine from one fleeting week to over a month.

Featured Neuroscience Open Neuroscience Articles Psychology

·December 4, 2018·6 min read

New Insights Into Loss of Pleasure in Depression

A new study reveals a brain region that contributes to anhedonia, the loss of pleasure, in those with depression. The study also shows how ketamine acts on this brain region, explaining why the drug appears to be so effective at treating anhedonia.