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ketamine

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Featured Neuroscience Psychology

·November 12, 2021·3 min read

New Target Identified for Rapid Antidepressant Drugs

Ketamine's rapid antidepressant action is due to specific synaptic effects, researchers report.

Featured Neuroscience Open Neuroscience Articles

·September 3, 2021·6 min read

Statistical Model Defines Ketamine Anesthesia’s Effects on the Brain

A new statistical model lays groundwork for understanding how ketamine induces an anesthetic response, steps to monitor unconscious patients, and provides new information about brain activity while unconscious.

Featured Neuroscience Neuroscience Videos Psychology

·August 30, 2021·3 min read

Brain Cells Conduct Antidepressant Action Even in the Absence of Activity

In the absence of neural activity, BDNF expression can still be activated. The findings shed light on how therapeutic ketamine used has an antidepressant effect and how it works in both the long and short term.

Featured Neuroscience Open Neuroscience Articles Psychology

·August 11, 2021·4 min read

New Findings on How Ketamine Prevents Depression

A new study provides novel mechanistic insights into how ketamine exerts its antidepressant effects for those with depression.

Featured Genetics Neuroscience Psychology

·July 28, 2021·3 min read

Discovery Points to Ketamine’s Long-Term Antidepressant Effects

The MeCP2 gene influences ketamine's behavioral effect and strengthens synapses, leading to an improvement in the drug's antidepressant effect over time.

Featured Neuroscience Psychology

·July 17, 2021·3 min read

Hope For Psychosis Sufferers

A new model of schizophrenia opens the door to a better understanding of, and therapeutic options for brain dysfunction that is at the root of psychosis.

Featured Neuroscience Open Neuroscience Articles

·July 6, 2021·4 min read

Rejuvenating Mouse Brains With Ketamine or Flickering Light

Ketamine and exposure to 60-hertz flickering light show promise as a potentially new, non-invasive therapy to help rejuvenate the aging brain.

Featured Neuroscience Psychology

·July 5, 2021·2 min read

Psychedelic Spurs Growth of Neural Connections Lost In Depression

One dose of psilocybin, the psychoactive compound found in magic mushrooms, increases dendritic spine density within 24 hours. The neurobiological changes lasted for a month following psilocybin exposure. Additionally, mice subjected to stress showed behavioral improvements and increased neurotransmitter activity after psilocybin exposure.

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Featured Neuroscience Psychology

·April 1, 2021·5 min read

Mice With Hallucination-Like Behaviors Reveal Insight Into Psychotic Illness

Mouse study reveals elevated dopamine levels preceded hallucination-like events, and artificially boosting dopamine levels induced more hallucination-like events. The behavioral effects could be blocked by administering haloperidol, an antipsychotic which blocks dopamine. The study sheds light on potential new treatments for psychotic disorders marked by hallucinations.

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Featured Neuroscience Psychology

·February 18, 2021·4 min read

New Information on the Effects of Antidepressants

SSRI's, ketamine, and tricyclic antidepressants all bind with TrkB. The findings challenge the roles serotonin and glutamate receptors play in the effects of antidepressant medications.

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Featured Neuroscience Psychology

·January 5, 2021·6 min read

Repeated Ketamine Infusions Reduce PTSD Symptom Severity

A series of ketamine infusions reduced PTSD symptoms by up to 30% from baseline compared to treatment with midazolam, which reduced symptoms by 20% over the same period. Ketamine treatment significantly reduced three of four PTSD associated symptoms, including intrusive thoughts, avoidance, and negative alterations in cognition and mood.