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          ketamine

          This is a drawing of a mouse against a psychedelic background
          FeaturedNeurosciencePsychology
          ·April 1, 2021·5 min read

          Mice With Hallucination-Like Behaviors Reveal Insight Into Psychotic Illness

          Mouse study reveals elevated dopamine levels preceded hallucination-like events, and artificially boosting dopamine levels induced more hallucination-like events. The behavioral effects could be blocked by administering haloperidol, an antipsychotic which blocks dopamine. The study sheds light on potential new treatments for psychotic disorders marked by hallucinations.
          Read More
          This shows a depressed looking young man
          FeaturedNeurosciencePsychology
          ·February 18, 2021·4 min read

          New Information on the Effects of Antidepressants

          SSRI's, ketamine, and tricyclic antidepressants all bind with TrkB. The findings challenge the roles serotonin and glutamate receptors play in the effects of antidepressant medications.
          Read More
          This shows a lot of heads in a spiral pattern
          FeaturedNeurosciencePsychology
          ·January 5, 2021·6 min read

          Repeated Ketamine Infusions Reduce PTSD Symptom Severity

          A series of ketamine infusions reduced PTSD symptoms by up to 30% from baseline compared to treatment with midazolam, which reduced symptoms by 20% over the same period. Ketamine treatment significantly reduced three of four PTSD associated symptoms, including intrusive thoughts, avoidance, and negative alterations in cognition and mood.
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          This shows a man sitting down
          FeaturedNeuroscienceNeuroscience VideosPsychology
          ·December 28, 2020·4 min read

          New Antidepressants Can Lift Depression and Suicidal Thoughts Fast, but Don’t Expect Magic Cures

          With the risk of potential for abuse, some new fast-acting antidepressants, like Ketamine, may not be a magic "cure-all" for depression.
          Read More
          This shows a depressed woman
          FeaturedNeurosciencePsychology
          ·December 16, 2020·4 min read

          How Does Ketamine Combat Depression?

          4E-BPs proteins are key to unlocking ketamine's antidepressant effects. When 4E-BPs are absent in neurons, ketamine can not produce its antidepressant effect.
          Read More
          This shows the different brain regions in a brain scan
          FeaturedNeuroscienceOpen Neuroscience ArticlesPsychology
          ·October 26, 2020·5 min read

          Single Brain Region Links Depression and Anxiety, Heart Disease, and Treatment Sensitivity

          Overactivity in the subgenual anterior cingulate cortex underlies several key symptoms of depression, anxiety, and heart disease.
          Read More
          This shows a brain
          FeaturedNeurosciencePsychology
          ·September 29, 2020·5 min read

          Computer Model Explains Altered Decision Making in Schizophrenia

          Summary: An artificial neural network has identified a potential mechanism for the impaired decision-making often seen in schizophrenia patients, which involves the reduced activity of NMDA receptors.
          Read More
          This shows a statue of a head with its face facing inward
          ElectrophysiologyFeaturedNeurosciencePsychology
          ·September 16, 2020·6 min read

          Brain Circuitry Underlying Dissociative Experiences Identified

          Researchers have identified a key neural circuit that plays a role in dissociation, a phenomenon in which people can feel disconnected from their bodies and reality.
          Read More
          This shows a bain
          FeaturedNeuroscienceOpen Neuroscience Articles
          ·June 11, 2020·5 min read

          High doses of ketamine can temporarily switch off the brain

          Higher doses of ketamine administered to sheep completely reduced brain activity for a short period. Researchers report as the drug wore off and consciousness was regained, the animals' brain activity switched between high and low-frequency oscillations. The timing of the brain activity corresponds to the time human users report experiencing feelings that their brain 'disconnected' from their bodies after ketamine use.
          Read More
          This shows a brain
          FeaturedNeurosciencePsychology
          ·June 5, 2020·3 min read

          NMDA receptors may link psychosis and sleep deficits

          NMDA receptor hypofunction is involved in the reduction of sleep spindles and delta oscillations, which appear in the brain during deep natural sleep. Findings confirm the role NMDA receptors play in sleep disorders that accompany psychotic states.
          Read More
          This shows a head
          FeaturedNeuroscienceOpen Neuroscience ArticlesPsychology
          ·June 1, 2020·4 min read

          How ketamine combats depression

          Ketamine increases the number of serotonin 1B receptors. Ketamine binds to serotonin 1B receptors, reducing the release of serotonin and increasing the release of dopamine.
          Read More
          This shows a woman's legs
          FeaturedNeuroscienceOpen Neuroscience ArticlesPsychology
          ·April 26, 2020·4 min read

          Effects of rapid-acting antidepressant ketamine consolidated in sleep?

          Brain connections strengthened with treatment from fast-acting antidepressants, such as ketamine, are consolidated during deep sleep. Researchers propose rapid antidepressant treatments share the ability to regulate both synaptic potentiation and homeostatic mechanisms, which may contribute to how the brain reorganizes its activity to defeat depression.
          Read More
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          This shows a child by a stove.

          Fumes from Indoor Cooking Fuels Linked to Developmental Delays

          This shows a woman resting.

          Mood Dips During Pill Pause

          This shows a woman.

          Visual Recognition Memory: Familiarity Decoded by Brief Spikes

          This shows a neuron.

          HSN Neuron Unravels Behavior Mysteries

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