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Karolinska Institute

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Featured Genetics Neuroscience Open Neuroscience Articles Psychology

·November 3, 2022·3 min read

Inflammation May Amplify Effect of Genetic Risk Variants for Schizophrenia

Pro-inflammatory cytokines IL-1 beta and IL-6 stimulate the expression of the schizophrenia-related C4A gene. Patients with high C4A expression displayed increased levels of IL-1 beta in cerebral spinal fluid samples. C4A levels were also correlated with markers of synaptic density. Findings reveal inflammation enhances the genetic risk variant for schizophrenia.

Autism Featured Neuroscience Psychology

·October 26, 2022·5 min read

Autistic Women Have Increased Risk of Mental Illness

Women on the autism spectrum are more likely to be diagnosed with a co-morbid mental health disorder, such as depression, anxiety, or increased risk of self-harm than males with autism.

This shows someone holding out a hand to help rescue a woman from a roof top

Featured Neuroscience Open Neuroscience Articles

·October 25, 2022·4 min read

Here’s How the Brain Works When We Choose to Help Someone in Danger

The same brain system that helps us to avoid danger is also activated during selfless, helping behaviors, allowing us to help others in danger.

Featured Neurology Neuroscience

·October 19, 2022·4 min read

COVID-19 Linked to Excessive Destruction of Connections Between Nerve Cells

COVID-19 infection causes microglia to excessively engulf synaptic structures and the upregulation of factors involved in phagocytosis.

Featured Neurology Neuroscience

·October 18, 2022·5 min read

Absence of Biomarker Profiles Typical of Alzheimer’s Disease

Findings highlight the need to continue developing new disease-modifying treatments with different mechanisms of action for patients with Alzheimer's disease.

Autism Featured Neuroscience

·September 7, 2022·6 min read

New Knowledge About the Link Between Infection During Pregnancy and Autism

Researchers discovered the link between autism and maternal infection does not appear to be causal. Results suggest the increased autism risks are more likely to be explained by shared familial factors including genetics or aspects of a shared environment.

Featured Neuroscience Psychology

·August 27, 2022·4 min read

Reducing Alcohol Consumption by Working Out

Both aerobic exercise and yoga reduce the desire to consume alcohol, a new study reports. Researchers found after one session of aerobic exercise people showed reduced cravings for alcohol, lower levels of stress, and improvements in mood.

Featured Neurology Neuroscience

·June 16, 2022·4 min read

Diabetes and Cardiovascular Disease Increase Dementia Risk

People with two of the diseases, type 2 diabetes, cardiovascular disease or stroke have double the risk of developing dementia, researchers say.

Featured Neuroscience Open Neuroscience Articles Pain Psychology

·June 13, 2022·4 min read

Brain Differences in Pain Modulation in People With Self-Injury Behavior

On average, women who self-harm have a higher tolerance to pain than those who do not self-injure. Brain scans revealed greater connectivity between brain areas involved in pain perception and pain modulation in those who self-harm.

Featured Neuroscience

·May 31, 2022·3 min read

Nerve Stimulation Promotes Resolution of Inflammation

Electrical stimulation of the vagus nerve promotes healing in those with acute inflammation by shifting the balance between inflammatory and anti-inflammatory molecules.

Featured Neuroscience Open Neuroscience Articles

·May 26, 2022·3 min read

Synaptic Connectivity of a Novel Cell Population in the Striatum

Researchers characterize a novel neural population within the striatum that appears to be responsible for the interplay between acetylcholine and GABA.