FeaturedGeneticsNeuroscience·March 21, 2023·5 min readTo Ward off Aging, Stem Cells Must Take Out the TrashBlood stem cells use an unexpected method to remove misfolded proteins, and the pathway's activity declines with age. However, boosting the aggrephagy pathway could help prevent age-related diseases.Read More
FeaturedGeneticsNeuroscienceVisual Neuroscience·March 17, 2023·3 min readCRISPR Gene-Editing Technique Reverses Vision Loss in MiceUsing a highly versatile form of CRISPR gene editing, researchers successfully restored vision in mice with retinitis pigmentosa.Read More
FeaturedGeneticsNeurologyNeuroscience·March 16, 2023·5 min readDNA Treatment Could Delay Paralysis That Strikes Nearly All Patients With ALSDNA designer therapeutics restored levels of a protein critical to motor neuron function, restoring the activity that is impaired as a result of ALS.Read More
FeaturedGeneticsNeuroscience·March 15, 2023·3 min readScientists Create Baby Mice from Two FathersUsing the genetic material from two male mice, researchers were able to successfully create baby mice. The advancement may eventually enable same-sex partners to have their own biological children.Read More
FeaturedGeneticsNeurosciencePsychology·March 15, 2023·3 min readMetabolic Disorder and Genetic Differences Associated With Female DepressionResearchers identified 11 areas of DNA that were linked to depression in women and one in males. They also found depression was associated with metabolic disease in women, providing an important new aspect to consider when treating depressive symptoms.Read More
FeaturedNeurologyNeurosciencePain·March 15, 2023·5 min readNew Test Quickly Identifies Patients Whose Postoperative Pain Can Be Effectively Treated by HypnosisA newly developed molecular diagnostic test is able to identify people who are most likely to benefit from hypnosis to help manage post-operative pain. This subset of highly hypnotizable people is also more likely to experience higher levels of post-operative pain.Read More
FeaturedGeneticsNeurosciencePsychology·March 13, 2023·3 min readNovel Genes That May Increase Risk for Schizophrenia IdentifiedA new study has identified two novel genes associated with schizophrenia, and a third new gene linked to an increased risk of autism and schizophrenia.Read More
AutismFeaturedGeneticsNeuroscience·March 10, 2023·5 min readCould an Ancient Virus Be a Genetic Driver of Autism?Genome and transcriptome analysis revealed BTBR autism mouse models have increased levels of endogenous retrovirus genes. BTBR/R models of ASD showed differences in the expression of a variety of genes that are indicative of endogenous retrovirus activation. BTBR/R mice exhibit autistic-like behaviors without reduced learning abilities.Read More
FeaturedGeneticsNeuroscience·March 8, 2023·4 min readHow Gene Expression Controls Synaptic Plasticity in the Aging Human BrainM1 muscarinic acetylcholine receptor (mAChR) dependent LTP and LTD share a common AMPA trafficking pathway. Either the upregulation of neurotransmitter receptor genes or suppression of the downregulation could improve synaptic dysfunction associated with age-related neurodegeneration. The findings could assist in the creation of new therapies for Alzheimer's disease that target synaptic plasticity.Read More
FeaturedGeneticsNeuroscienceOpen Neuroscience Articles·March 8, 2023·4 min readModifying Messenger RNA May Provide a New Target for Alzheimer’s DiseaseTargeting and reducing the methylation of a key mRNA promoted the migration of macrophages in the brain and can improve cognitive symptoms of Alzheimer's disease.Read More
FeaturedNeuroscienceOpen Neuroscience ArticlesPsychology·March 7, 2023·4 min readBlood Test for Anxiety DevelopedA newly developed blood test screens for biomarkers associated with anxiety to determine a person's risk of developing the disorder as well as monitor the severity of symptoms in those with anxiety.Read More
FeaturedGeneticsNeurosciencePsychology·March 3, 2023·3 min readA Blood Factor Involved in DepressionIn adults, levels of GDF11, a gene that is key to the regeneration of murine neural stem cells, are inversely related to depressive episodes. Administering the GDF11 proteins to aging mice reduced depressive states and improved cognition.Read More
