Sleep deprivation reduces the brain's ability to unlearn fear-related memories, a new study reports.
The expression of the CREB gene may function as a switch to regulate fear and extinction learning. The findings could provide a new avenue of treatment for PTSD and other mental health disorders.
Study reveals a key role for the ventromedial hypothalamus in fight or flight behaviors. Findings suggest the ventromedial hypothalamus alters in response to social experiences.
Haunted house experiment shows "just the right" amount of fear is key to maximizing enjoyment.
Study provides contrary evidence to existing theory, finding anxiety and fear reflect overlapping neural circuits.
When a mouse senses a threat, neurons in the ventromedial hypothalamus become activated and remain active for ten seconds after the threat is removed. Fear responses could be induced by artificially stimulating these neurons. Artificially silencing the neurons reduced fear behavior.
Repetitive transcranial memory stimulation applied to the dorsolateral prefrontal cortex modifies the negative effects of fear memories. The findings could have implications for the treatment of PTSD.