According to a new study, the most common genetic cause of Parkinson’s is not only responsible for the condition’s distinctive movement problems but may also affect vision.
Researchers suggest the overexpression of a protein called alpha-synuclein appears to disrupt vital recycling processes in neurons. The study may have major implications for more fully understanding the causes and mechanisms of Parkinson’s disease.
Researchers identify a protein trafficking defect within brain cells that may underlie common non-familial forms of Parkinson’s disease. The study implicates two genetic variants that disrupt protein sorting in neurons.
A new study shows a complex set of overlapping neuronal circuits works in concert to drive temperature preferences in the fruit fly Drosophila by affecting a single target, a heavy bundle of neurons within the fly brain known as the mushroom body. These nerve bundles play critical roles in learning and memory.
With a new insight into a model of Parkinson’s disease, researchers have identified a novel target for mitigating some of the disease’s toll on the brain.
The work will be conducted on laboratory rats modelling Parkinson’s disease. The transplanted cells will be derived from skin from an adult human and will have been “reprogrammed” as nerve cells. The light-sensitive protein is obtained from a bacterium, which uses light to gain energy.
Stem cell study may help to unravel how a genetic mutation leads to Parkinson's symptoms. By reprogramming skin cells from Parkinson's disease patients with a known genetic mutation, researchers identified damage to neural stem cells as a powerful player in Parkinson's disease.
Researchers recently localised and identified the most important types of nerve cells involved in forming positive and negative memories of a fruit fly. All four nerve cell types they discovered use dopamine to communicate with other nerve cells. Three of the nerve cell types assume various functions in mediating negative stimuli, while the fourth enables the fly to form positive memories.
Researchers at Yale School of Medicine have zeroed in on a set of neurons in the part of the brain...
New evidence that receptors for brain’s ‘reward’ chemical provide protection. Brain scans of two strains of mice imbibing significant quantities...