Signal blocks stem cell division in the geriatric brain
A gene regulated called Id4 appears to be a key component in controlling stem cell proliferation. ... Read More...
dentate gyrus
Alzheimer’s drug reverses brain damage from adolescent alcohol exposure
Donepezil, a drug routinely administered to slow cognitive decline in Alzheimer's disease, shows promise in treating damage caused to the brain by adolescent alcohol exposure. The drug reverses neuroinflammation and neuron damage in rats exposed to alcohol during adolescence. ... Read More...
Negative memory storage affects depression symptoms
Enhanced reactivation of negative memory engrams may be an important cellular mechanism behind the cognitive symptoms of depression.... Read More...
Exosomes may hold the answer to treating and diagnosing developmental brain disorders
Exosomes carry signaling information required to regulate neural circuit development.... Read More...
Exercise fine-tunes brain’s connections, eases autism spectrum disorder in mouse model
Participating in exercise improved synaptic pruning in mouse models of autism. The study also found microglia dependant synaptic pruning is impaired by maternal inflammation, which has been previously connected to the development of ASD. ... Read More...
Broken brain cells repaired in dementia mouse model
Chemically activating neurons and placing mice in stimulating environments reverses alterations and restores some neural connectivity in frontotemporal dementia. If translated into humans, the findings could help develop new treatments for fighting the effects of dementia in the elderly.... Read More...
Proof it’s possible to enhance or suppress memories
Using optogenetics to stimulate different areas of the hippocampus has the ability to enhance or suppress memories in mice. The findings could have implications for suppressing memories associated with traumatic events in PTSD, and also in enhancing cognitive ability or improving memory for those with neurodegenerative diseases, in the future. ... Read More...
How the brain fights off fears that return to haunt us
Newly identified 'extinction neurons' in the hippocampus suppress fearful memories when activated, and allow the memories to return when deactivated. The findings may provide new treatment avenues for PTSD, phobias, and anxiety.... Read More...
Single Population of Stem Cells Contributes to Lifelong Hippocampal Neurogenesis: Mouse Study
The findings support a continuous model of neurogenesis throughout development and adulthood.... Read More...
Three Ways Studying Organic Chemistry Changes the Brain
Summary: Using three different types of brain imaging, the researchers found evidence of the three types of changes in the brain, all occurring in exactly the s... Read More...
Lessons Learned From the Adult Neurogenesis Debate
A new paper looks at the controversies surrounding adult neurogenesis.... Read More...
Reversing Memory Loss: Mouse Study
Researchers report osterocalcin, a naturally occurring hormone, can help boost memory in aging mice. The findings pave the way for new treatments to help stave off, and possibly reverse memory loss in humans.... Read More...