Exosomes may hold the answer to treating and diagnosing developmental brain disorders
Exosomes carry signaling information required to regulate neural circuit development.... Read More...
dentate gyrus
Exercise fine-tunes brain’s connections, eases autism spectrum disorder in mouse model
Participating in exercise improved synaptic pruning in mouse models of autism. The study also found microglia dependant synaptic pruning is impaired by maternal inflammation, which has been previously connected to the development of ASD. ... Read More...
Broken brain cells repaired in dementia mouse model
Chemically activating neurons and placing mice in stimulating environments reverses alterations and restores some neural connectivity in frontotemporal dementia. If translated into humans, the findings could help develop new treatments for fighting the effects of dementia in the elderly.... Read More...
Proof it’s possible to enhance or suppress memories
Using optogenetics to stimulate different areas of the hippocampus has the ability to enhance or suppress memories in mice. The findings could have implications for suppressing memories associated with traumatic events in PTSD, and also in enhancing cognitive ability or improving memory for those with neurodegenerative diseases, in the future. ... Read More...
How the brain fights off fears that return to haunt us
Newly identified 'extinction neurons' in the hippocampus suppress fearful memories when activated, and allow the memories to return when deactivated. The findings may provide new treatment avenues for PTSD, phobias, and anxiety.... Read More...
Single Population of Stem Cells Contributes to Lifelong Hippocampal Neurogenesis: Mouse Study
The findings support a continuous model of neurogenesis throughout development and adulthood.... Read More...
Three Ways Studying Organic Chemistry Changes the Brain
Summary: Using three different types of brain imaging, the researchers found evidence of the three types of changes in the brain, all occurring in exactly the s... Read More...
Lessons Learned From the Adult Neurogenesis Debate
A new paper looks at the controversies surrounding adult neurogenesis.... Read More...
Reversing Memory Loss: Mouse Study
Researchers report osterocalcin, a naturally occurring hormone, can help boost memory in aging mice. The findings pave the way for new treatments to help stave off, and possibly reverse memory loss in humans.... Read More...
Even Mild Physical Activity Immediately Improves Memory Function
A new study reports participating in light physical activity, such as yoga or tai chi, can help to increase connectivity between brain areas responsible for memory formation and storage.... Read More...
An Ion Channel Differentiates Newborn and Mature Neurons in the Adult Brain
Researchers report newborn granule cells in the dentate gyrus become less excitable after three weeks. The loss of excitability is crucial for the functioning of mature neurons.... Read More...
Alzheimer’s Risk Gene Impairs Neurogenesis: Mouse Study
A new mouse study finds APOE genes, commonly associated with Alzheimer's disease, impairs the development of new neurons in areas of the brain associated with memory.... Read More...