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dentate gyrus

Featured Neuroscience Open Neuroscience Articles

·April 20, 2016·5 min read

A New Role For Immature Granule Cells in the Dentate Gyrus

A new study proposes a model for how immature neurons in the dentate gyrus appear to enhance pattern separation.

Featured Genetics Neuroscience

·January 20, 2020·2 min read

A new role for neurogenesis

Dentate gyrus neurogenesis acts to replace lost neurons and restore function following massive neuron loss.

Featured Neuroscience

·October 24, 2017·7 min read

A New Theory of Memory Formation

Researchers propose a new theory of memory formation, reporting memory storage does not rely on the strengthening of connection between memory cells, but on the pattern of connections that form within the first few minutes of an event.

Featured Neuroscience Open Neuroscience Articles

·September 14, 2022·4 min read

A Switch Telling the Brain When to Learn and When to Remember

Study reveals a neural signal in the hippocampus that enables the brain to alternate between learning and remembering modes.

Image shows granuel cells in a mouse dentate gyrus.

Featured Neuroscience

·March 10, 2016·5 min read

Adult Born Granule Cells Critical For Memory Formation

Adult born granule cells appear to play a key role in memory encoding, a new study reports.

Featured Neuroscience

·June 22, 2020·3 min read

Adult-born neurons grow more than their infancy-born counterparts

Neurons created as a result of adult neurogenesis mature for longer and grow larger than those created during infancy. Findings suggest adult-born neurons may have a more powerful function than those created during infancy and may play a critical role in neuroplasticity.

Electrophysiology Featured Neuroscience Psychology

·February 19, 2020·5 min read

Altered potassium levels in neurons may cause mood swings in bipolar disorder

Increased potassium currents were responsible for hyperactivity of CA3 neurons. When exposed to potassium channel blockers, the hyperactivity disappeared. However, when exposed to lithium, the drug not only reversed hyperactivity but reduced potassium currents at the same time. The findings strengthen the case that potassium currents play a role in bipolar disorder.

Featured Neurology

·February 15, 2018·5 min read

Alzheimer’s Drug Repairs Brain Damage After Alcohol Binges: Rat Study

Researchers report a drug used to slow cognitive decline in Alzheimer's disease may help to reverse memory and learning problems in teens who binge drink.

Featured Neuroscience Open Neuroscience Articles

·August 20, 2019·4 min read

Alzheimer’s drug reverses brain damage from adolescent alcohol exposure

Donepezil, a drug routinely administered to slow cognitive decline in Alzheimer's disease, shows promise in treating damage caused to the brain by adolescent alcohol exposure. The drug reverses neuroinflammation and neuron damage in rats exposed to alcohol during adolescence.

Featured Genetics Neurology Neuroscience

·July 30, 2018·2 min read

Alzheimer’s Risk Gene Impairs Neurogenesis: Mouse Study

A new mouse study finds APOE genes, commonly associated with Alzheimer's disease, impairs the development of new neurons in areas of the brain associated with memory.

Featured Neuroscience

·August 11, 2018·5 min read

An Ion Channel Differentiates Newborn and Mature Neurons in the Adult Brain

Researchers report newborn granule cells in the dentate gyrus become less excitable after three weeks. The loss of excitability is crucial for the functioning of mature neurons.